Molecular Genetic and Pathological Studies of Anal Tumors
To determine the status of previously identified anal cancer molecular markers and any
correlations with outcome as well as to discover new molecular biomarkers through
correlating molecular data with clinical outcome. Study of tissue samples and cells from
biopsies of your lesion and blood sample. We hope to learn the role genes and proteins may
play in the development of anal cancer. Experiments will be performed using this tissue and
blood, include analysis of DNA, analysis of RNA expression levels, analysis of protein
levels of important gene products, and development of tissue culture cell lines.
Observational Model: Case-Only, Time Perspective: Prospective
Genetic analysis of blood sample as well as tissues , will provide us with any possible tumor marker for a better prognostic indicator.
Mark Lane Welton
United States: Institutional Review Board
|Stanford University School of Medicine||Stanford, California 94305-5317|