Molecular Genetic and Pathological Studies of Anal Tumors
18 Years
N/A
Both
Rectal Cancer, Colon Cancer, Colonic Neoplasms, Anal Cancer
Trial Information
Molecular Genetic and Pathological Studies of Anal Tumors
To determine the status of previously identified anal cancer molecular markers and any
correlations with outcome as well as to discover new molecular biomarkers through
correlating molecular data with clinical outcome. Study of tissue samples and cells from
biopsies of your lesion and blood sample. We hope to learn the role genes and proteins may
play in the development of anal cancer. Experiments will be performed using this tissue and
blood, include analysis of DNA, analysis of RNA expression levels, analysis of protein
levels of important gene products, and development of tissue culture cell lines.
Inclusion Criteria:
Inclusion Criteria:
- Patients with anal tumors
- Undergoing surgery for elective colon and rectal surgery
Exclusion Criteria:No other patients other than adult patients with anal cancer or high
risk for anal cancer refered to Stanford will be enrolled to the study. No Children will
be included to the study
Type of Study:
Observational
Study Design:
Observational Model: Case-Only, Time Perspective: Prospective
Outcome Measure:
Genetic analysis of blood sample as well as tissues , will provide us with any possible tumor marker for a better prognostic indicator.
Outcome Time Frame:
Annual assessment.
Safety Issue:
No
Principal Investigator
Mark Lane Welton
Investigator Role:
Principal Investigator
Investigator Affiliation:
Stanford University
Authority:
United States: Institutional Review Board
Study ID:
ANAL0001
NCT ID:
NCT00267787
Start Date:
September 2004
Completion Date:
December 2013
Related Keywords:
- Rectal Cancer
- Colon Cancer
- Colonic Neoplasms
- Anal Cancer
- Anus Neoplasms
- Neoplasms
- Colonic Neoplasms
- Rectal Neoplasms
Name | Location |
|---|---|
| Stanford University School of Medicine | Stanford, California 94305-5317 |
