Inclusion Criteria:

- ECOG 0-1

- Patients with histologically proven epidermoid carcinoma or adenocarcinoma of
esophagus or stomach, with unresectable or metastatic disease;

- No previous treatment with chemotherapy or radiotherapy

- Measurable lesion (uni or bidimensional)

Exclusion Criteria:

- Creatinin clearance <50 mL/min

- Total bilirubin >1.5*ULN (Upper Limit of Normal)

- AST/ALT > 2.5*ULN

- Total White Blood Cell <1.500.000/mL

- Platelet count <100.000.000/mL

- symptomatic sensitive peripheral neuropathy

- pregnant or breast-feeding women

The above information is not intended to contain all considerations relevant to a
patient's potential participation in a clinical trial.