Inclusion Criteria:

- Radical prostatectomy for prostate cancer within last 2 months.

- Post-operative Kattan nomogram predicts >25% risk of PSA relapse by 5 years.

- 6-week post-operative serum PSA<0.2ng/mL.

- Low levels of circulating prostate cancer cells in the blood, detected by PCR
amplification of PSA mRNA 6 weeks post-prostatectomy.

Exclusion Criteria:

- Pre-operative serum PSA level >20ng/ml.

- Clinical evidence of metastases by 6-week post-operative visit.

- Prior treatment with either ADT or bisphosphonate therapy.

- Current active dental problems including infection of the teeth or jawbone (maxilla
or mandibular); dental or fixture trauma, or a current or prior diagnosis of
osteonecrosis of the jaw (ONJ), of exposed bone in the mouth, or of slow healing
after dental procedures.

- Recent (within 6 weeks) or planned dental or jaw surgery (e.g.extraction, implants)

Other protocol defined inclusion / exclusion criteria may apply.