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16 Years
Open (Enrolling)
Lung Cancer

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Trial Information

The staging of lung cancer was according to tumor size, involvement of lymph node and
metastatic status. But there is a different prognosis in cancer patients of the same stage.
The coagulation status of cancer patients was considered as an important possible prognostic
factor. So in this study, we want to evaluate patients' coagulation status and find the
relation of coagulation status and cancer status.

We thus propose a prospective study using coagulation factors in order to search for the
relationship between cancer stage and pre-coagulation status in Taiwanese lung cancer
patients. We will also evaluate the potential use of tissue factor as a prognosis predictor
in lung cancer patients.

Inclusion Criteria:

- Patients with newly-diagnosed lung cancer

- Serum from cancer-free healthy volunteers

Exclusion Criteria:

- Chronic renal failure or end-stage renal disease [ESRD] (creatinine [Cr] > 2 )

- Hyperlipidemia on statin therapy

- Acute myocardial infarction

- Tapal or Plavix use

- Active thromboembolic event

- Severe liver disease (> child B)

Type of Study:


Study Design:

Allocation: Random Sample, Observational Model: Natural History, Time Perspective: Cross-Sectional, Time Perspective: Prospective

Principal Investigator

Chong-Jen Yu, M.D., Ph.D.

Investigator Role:

Principal Investigator

Investigator Affiliation:

National Taiwan University Hospital


Taiwan: Department of Health

Study ID:




Start Date:

June 2005

Completion Date:

Related Keywords:

  • Lung Cancer
  • Tissue factor
  • Lung cancer
  • Tissue factor protein inhibitor
  • Factor VII
  • Factor X
  • Lung Neoplasms