Role of Soy Isoflavones in Prostate Cancer Prevention
This is a randomized study evaluating the effetiveness and direct effect a commercial soy
suplement has on prostate cancer and normal prostate tissue. Patients will be randomized to
either receive placebo or a comercial soy supplement for 2-4 weeks prior to the planned
surgery for treatment of their prostate cancer. The specific objectives are:
1. To assess the effect of soy supplementation on endogenous hormone production levels and
serum prostate specific antigens.
2. To assess the impact of soy supplementation on estrogen receptor expression(ER).
3. To determine the impact of soy isoflavones on cell cycle regulation and associated gene
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Prevention
1.Effect of Soy Isoflavones on serum hormonal serum levels.
Peter Vanveldhuizen, MD
VA Medical Center, Kansas City MO
United States: Federal Government
|VA Medical Center, Kansas City MO||Kansas City, Missouri 64128|