This study is designed to investigate the epidemiologic, genetic, laboratory and clinical
characterization of individuals with cancer (gastric, colorectal, esophageal, liver,
prostate, lung, breast and endometrial cancer, etc.). We will accrue approximately 1600
patients as experimental group. The control group consists of subjects who will be confirmed
without cancer. We will explore the environmental (including family history, life style,
diet, physical activity, neuropsychological functioning,plasma levels of oxidative stress
factors, angiogenic factors, and tumor markers, etc.) and genetic (including oxidative
stress factors and angiogenic factors, etc.) risk factors. We will study the association
between various environmental risk factors with the clinical characterization and
correlation between the genetic polymorphisms and the presence of various cancer.
Observational
Observational Model: Case Control, Observational Model: Natural History, Time Perspective: Cross-Sectional, Time Perspective: Retrospective
Bin Wang, Ph.D
Principal Investigator
Department of Pharmacology, Institute of Clinical Pharmacology, Nanjing Medical University
China: Ethics Committee
ICP036
NCT00251563
August 2005
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