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N/A
18 Years
89 Years
Open (Enrolling)
Both
Ocular Diseases

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Trial Information


This study is designed to investigate the epidemiologic, genetic, laboratory and clinical
characterization of individuals with ocular diseases (cataract, retinopathy, age-related
macular degeneration, glaucoma, retinal detachment, ocular tumor, etc.). We will accrue
approximately 800 patients as experimental group. The control group consists of age/sex
frequency-matched subjects who will be confirmed without ocular diseases. We will explore
the environmental (including family history, life style, diet, physical activity,
neuropsychological functioning´╝îplasma levels of oxidative stress and angiogenic factors,
etc.) and genetic (including oxidative stress and angiogenic factors, etc.) risk factors. We
will study the association between various environmental risk factors with the clinical
characterization and correlation between the genetic polymorphisms and the presence of
various ocular diseases.


Inclusion Criteria:



- This is a study only of Chinese.

- Subjects will be allowed to participate if they self-identify as Chinese.

- Individuals with ocular diseases (cataract, retinopathy, age-related macular
degeneration, glaucoma, retinal detachment, ocular tumor, etc.) will be allowed to
participate. To participate in the study as the control, subjects should be confirmed
without ocular diseases.

Type of Study:

Observational

Study Design:

N/A

Principal Investigator

Bin Wang, Ph.D

Investigator Role:

Principal Investigator

Investigator Affiliation:

Department of Pharmacology, Institute of Clinical Pharmacology, Nanjing Medical University

Authority:

China: Ethics Committee

Study ID:

ICP008

NCT ID:

NCT00249392

Start Date:

October 2004

Completion Date:

Related Keywords:

  • Ocular Diseases
  • ocular diseases
  • risk factors
  • genetic factors

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