This study is designed to investigate the epidemiologic, genetic, laboratory and clinical
characterization of individuals with ocular diseases (cataract, retinopathy, age-related
macular degeneration, glaucoma, retinal detachment, ocular tumor, etc.). We will accrue
approximately 800 patients as experimental group. The control group consists of age/sex
frequency-matched subjects who will be confirmed without ocular diseases. We will explore
the environmental (including family history, life style, diet, physical activity,
neuropsychological functioning,plasma levels of oxidative stress and angiogenic factors,
etc.) and genetic (including oxidative stress and angiogenic factors, etc.) risk factors. We
will study the association between various environmental risk factors with the clinical
characterization and correlation between the genetic polymorphisms and the presence of
various ocular diseases.
Observational
N/A
Bin Wang, Ph.D
Principal Investigator
Department of Pharmacology, Institute of Clinical Pharmacology, Nanjing Medical University
China: Ethics Committee
ICP008
NCT00249392
October 2004
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