Inclusion Criteria:

- Histologic diagnosis of Stage I, II or III cancer (chemotherapy naïve for breast
cancer) with anthracycline-based adjuvant chemotherapy with or without a taxane

- Hemoglobin >=9 and <=14 g/dL unrelated to transfusion

- Able to read, understand and complete QoL & Cognition tools

- Patients with reproductive potential must have a negative serum pregnancy test within
7 days of study enrollment and use an adequate contraceptive method

Exclusion Criteria:

- Patients who will receive more than a total of 24 weeks of chemotherapy

- psychiatric or neurologic condition that would prevent informed consent and
completion of questionnaires or that is poorly controlled with the current treatment
regimen

- severe hemiparesis or other condition, distal neuropathy, action tremor or other
motor dysfunction, visual deficiencies preventing/decrease bimanual keyboard
operation

- severe bradyphrenia (slow thinking) or bradykinesia (slow movement)