Acupressure and Relaxation for Nausea Control
This study hypothesizes that patients receiving efficacy enhancing information about the
acupressure bands will expect less treatment-related nausea, which will subsequently result
in less treatment-related nausea compared to patients who do not receive such information.
This study extends prior research by utilizing a randomized controlled trial in a clinical
environment to examine the efficacy of an intervention that is specifically designed to
reduce patients' response expectancies concerning nausea development from cancer treatments,
and, thereby, reduce nausea.
The objectives of this study are as follow:
1. To provide preliminary data on whether a two-tiered strategy to increase patients'
expectancies for nausea prevention and/or management will result in reduced
2. To provide preliminary data on whether a two-tiered strategy to increase patients'
expectancies for nausea prevention and/or management will result in increased
health-related quality of life (HRQL) in patients receiving emetogenic chemotherapy.
To provide preliminary data on whether a two-tiered strategy to increase patients'
expectancies for nausea prevention and/or management is more effective than a single-tiered
strategy in reducing chemotherapy- induced nausea.
The study contains the following arms:
1. Control handout and control tape.
2. Active handout and control tape.
3. Control handout and active tape.
4. Active handout and active tape.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Supportive Care
Five-day Nausea Diary
Nausea was measured using a five-day patient report diary. Each day was divided into 4 sections: morning, afternoon, evening, and night. Patients reported severity of nausea for each period daily. Severity of nausea was assessed on a 7-point rating scale, anchored at one end by 1 = "Not at all nauseated" and at the other end by 7 = "Extremely nauseated." The description "Moderately nauseated" was centered on the scale below the 4. Average Nausea was the mean severity for the 20 reporting periods.
Joseph A Roscoe, PhD
University of Rochester
United States: Institutional Review Board
|University of Rochester James P. Wilmot Cancer Center||Rochester, New York 14642|