Implicit Learning, Comorbidity and Stress Vulnerability in Chronic Functional Pain Syndromes
20 Years
70 Years
Both
Fibromyalgia, Irritable Bowel Syndrome
Trial Information
Implicit Learning, Comorbidity and Stress Vulnerability in Chronic Functional Pain Syndromes
Study 1: Implicit operant learning of sensitization and habituation in an experimental heat
pain model will be investigated and compared in healthy controls, chronic pain patients with
fibromyalgia, with and w/o visceral pain.
Study 2: Functional imaging of implicit operant learning of sensitization and habituation in
an experimental heat pain model (same subgroups as in study 1).
Inclusion Criteria:
- Fibromyalgia according to American College of Rheumatology (ACR) criteria
- Visceral hypersensitivity according to ROME criteria
- Chronic pain according to International Association for the Study of Pain (IASP)
criteria
Exclusion Criteria:
- Abnormal quantitative sensory testing
- Psychiatric or neurological anamnesis, except fear and depression
- Acute major depression
- Substance abuse
Type of Study:
Interventional
Study Design:
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind, Primary Purpose: Diagnostic
Principal Investigator
Rupert Hoelzl, Prof. Dr. phil.
Investigator Role:
Study Director
Investigator Affiliation:
University of Mannheim
Authority:
Germany: Deutsche Forschungsgemeinschaft (DFG)
Study ID:
DFG HO 904/11-3,4
NCT ID:
NCT00222209
Start Date:
September 2005
Completion Date:
November 2007
Related Keywords:
- Fibromyalgia
- Irritable Bowel Syndrome
- Experimental study
- chronic pain
- operant learning
- comorbidity
- stress
- Fibromyalgia w visceral hypersensitivity
- Fibromyalgia w/o visceral hypersensitivity
- Fibromyalgia
- Myofascial Pain Syndromes
- Irritable Bowel Syndrome
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