Long-Term Study of the Efficacy and Safety of Lansoprazole in the Treatment of Zollinger-Ellison and Other Acid Hypersecretors
19 Years
N/A
Both
Zollinger-Ellison Syndrome, Multiple Endocrine Neoplasia
Trial Information
Long-Term Study of the Efficacy and Safety of Lansoprazole in the Treatment of Zollinger-Ellison and Other Acid Hypersecretors
The aim of this protocol is to study the medical management of acid hypersecretory states
including Zollinger-Ellison using Prevacid. The immediate objective is to heal peptic ulcers
and eliminate symptoms and in the long term to prevent relapse of symptoms, lesions and
complications. Other objectives include observation of the efficacy in controlling gastric
acid production and of the safety of high dose, long-term use of Prevacid.
Inclusion Criteria:
- Diagnosed with Zollinger-Ellison syndrome
Exclusion Criteria:
- Pregnant or lactating females
Type of Study:
Interventional
Study Design:
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Outcome Measure:
Long-term Medical(Non-surgical)Control of Gastric Acid Production Assessed From Time of Study Enrollment, up to 240 Months Post Enrollment.
Outcome Description:
number of participants with control of gastric acid production
Outcome Time Frame:
up to 240 months from study enrollment
Safety Issue:
No
Principal Investigator
C. Mel Wilcox, M.D.
Investigator Role:
Principal Investigator
Investigator Affiliation:
University of Alabama at Birmingham
Authority:
United States: Institutional Review Board
Study ID:
F030107005
NCT ID:
NCT00204373
Start Date:
March 2003
Completion Date:
December 2010
Related Keywords:
- Zollinger-Ellison Syndrome
- Multiple Endocrine Neoplasia
- Neoplasms
- Endocrine Gland Neoplasms
- Multiple Endocrine Neoplasia
- Zollinger-Ellison Syndrome
- Gastrinoma
Name | Location |
|---|
