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The Roles of Tissue Factor in Malignant Gliomas


N/A
18 Years
N/A
Not Enrolling
Both
Venous Thromboembolism, Brain Tumors

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Trial Information

The Roles of Tissue Factor in Malignant Gliomas


To explore the relationship between tissue factor levels, tumour progression, activation of
blood coagulation and venous thromboembolism with malignant glioma


Inclusion Criteria:



- participation in PRODIGE

- adult patients

- newly diagnosed, biopsy-confirmed grade III/IV malignant gliomas

- undergone craniotomy or stereotactic biopsy > 2 days and < 4 weeks before

Exclusion Criteria:

- have known hereditary thrombophilia

- are receiving experimental antiangiogenic therapy

Type of Study:

Observational

Study Design:

Observational Model: Defined Population, Observational Model: Natural History, Time Perspective: Longitudinal, Time Perspective: Prospective

Principal Investigator

Agnes Lee, MD

Investigator Role:

Study Chair

Investigator Affiliation:

Hamilton Health Sciences and McMaster University

Authority:

Canada: Health Canada

Study ID:

OCOG-2003-TFsubstudy

NCT ID:

NCT00201903

Start Date:

January 2004

Completion Date:

October 2006

Related Keywords:

  • Venous Thromboembolism
  • Brain Tumors
  • venous thromboembolism
  • brain tumours
  • glioma
  • tissue factor
  • blood coagulation
  • tumour progression
  • low molecular weight heparin
  • Brain Neoplasms
  • Glioma
  • Thromboembolism
  • Venous Thromboembolism
  • Venous Thrombosis

Name

Location

Henry Ford Hospital Detroit, Michigan  48202
Huntsman Cancer Institute Salt Lake City, Utah  84112