Trial Information
The Roles of Tissue Factor in Malignant Gliomas
To explore the relationship between tissue factor levels, tumour progression, activation of
blood coagulation and venous thromboembolism with malignant glioma
Inclusion Criteria:
- participation in PRODIGE
- adult patients
- newly diagnosed, biopsy-confirmed grade III/IV malignant gliomas
- undergone craniotomy or stereotactic biopsy > 2 days and < 4 weeks before
Exclusion Criteria:
- have known hereditary thrombophilia
- are receiving experimental antiangiogenic therapy
Type of Study:
Observational
Study Design:
Observational Model: Defined Population, Observational Model: Natural History, Time Perspective: Longitudinal, Time Perspective: Prospective
Principal Investigator
Agnes Lee, MD
Investigator Role:
Study Chair
Investigator Affiliation:
Hamilton Health Sciences and McMaster University
Authority:
Canada: Health Canada
Study ID:
OCOG-2003-TFsubstudy
NCT ID:
NCT00201903
Start Date:
January 2004
Completion Date:
October 2006
Related Keywords:
- Venous Thromboembolism
- Brain Tumors
- venous thromboembolism
- brain tumours
- glioma
- tissue factor
- blood coagulation
- tumour progression
- low molecular weight heparin
- Brain Neoplasms
- Glioma
- Thromboembolism
- Venous Thromboembolism
- Venous Thrombosis
Name | Location |
Henry Ford Hospital |
Detroit, Michigan 48202 |
Huntsman Cancer Institute |
Salt Lake City, Utah 84112 |