Effect of N-Acetylcysteine on Skeletal Muscle in Cachectic Cancer Patients Undergoing a Resistance Training Program (Phase 2 Study)
Phase 2
20 Years
80 Years
20 Years
80 Years
Not Enrolling
Both
Gastrointestinal Neoplasms, Bronchial Carcinoma, Hodgkin Disease, Non-Hodgkin Lymphoma, Weight Loss
Both
Gastrointestinal Neoplasms, Bronchial Carcinoma, Hodgkin Disease, Non-Hodgkin Lymphoma, Weight Loss
Trial Information
Effect of N-Acetylcysteine on Skeletal Muscle in Cachectic Cancer Patients Undergoing a Resistance Training Program (Phase 2 Study)
Inclusion Criteria:
- gastrointestinal or bronchial cancer
- weight loss of 10% within 6 months
- sufficient mobility
Exclusion Criteria:
- severe pain, steroid therapy, severe internal, muscular, neurological, psychiatric
disease, N-acetylcysteine allergy
Type of Study:
Interventional
Study Design:
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment
Outcome Measure:
muscle cross-sectional area, peak forces
Principal Investigator
Wulf Hildebrandt, MD
Investigator Role:
Study Director
Investigator Affiliation:
German Cancer Research Center
Authority:
Germany: Federal Institute for Drugs and Medical Devices
Study ID:
whilde157/2003
NCT ID:
NCT00196885
Start Date:
December 2003
Completion Date:
December 2006
Related Keywords:
- Gastrointestinal Neoplasms
- Bronchial Carcinoma
- Hodgkin Disease
- Non-Hodgkin Lymphoma
- Weight Loss
- cancer cachexia
- muscle wasting
- weight loss
- proteolysis
- Neoplasms
- Carcinoma
- Carcinoma, Bronchogenic
- Gastrointestinal Neoplasms
- Digestive System Neoplasms
- Hodgkin Disease
- Lymphoma
- Lymphoma, Non-Hodgkin
- Weight Loss
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