Know Cancer

or
forgot password

Pilot Study to Investigate the Feasibility of Optical Spectroscopy to Quantify Bulk Breast Tissue Properties in Girls Age 10 - 14 Years


N/A
10 Years
14 Years
Not Enrolling
Female
Breast Cancer

Thank you

Trial Information

Pilot Study to Investigate the Feasibility of Optical Spectroscopy to Quantify Bulk Breast Tissue Properties in Girls Age 10 - 14 Years


The period between menarche and the age of first full-term pregnancy has been identified as
being most crucial for establishing an individual's future breast cancer risk.
Epidemiological studies further suggest exposures, such as foods and toxins, during
adolescence to have a significant impact on the likelihood of transformation in the
developing breast resulting in cancer later in life. Adolescent diet affects mammary
development directly and indirectly by influencing the micronutrients and the hormonal
status of the adolescent. The goal of this study is to investigate the feasibility of
Optical Spectroscopy (OS), a method based on differential light scattering and absorption in
tissue, to quantify bulk breast tissue properties in adolescent females.

Inclusion Criteria


Inclusion Criteria (Girls):

- Are in good health and are able to provide assent

- Are between the ages of 10 and 14

- Are interested in participating in this study

- Are willing to come, accompanied by a parent, to the Princess Margaret Hospital

Inclusion Criteria (Parents):

- Are able to provide consent

- Are willing to accompany your daughter to the Princess Margaret Hospital for one
visit of about 45 minutes

Exclusion Criteria (Girls):

- Have had previous surgeries to the chest area

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Cross-Sectional

Principal Investigator

Lothar Lilge, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada M5G 2M9; Department of Biophysics and Bioimaging, University of Toronto, Toronto, Ontario, Canada M5G 2M9

Authority:

Canada: Health Canada

Study ID:

UHNREB#05-0154-CE

NCT ID:

NCT00188591

Start Date:

April 2005

Completion Date:

November 2008

Related Keywords:

  • Breast Cancer
  • Optical Transillumination Spectroscopy
  • Breast Cancer Risk
  • Breast Neoplasms

Name

Location