Pilot Study to Investigate the Feasibility of Optical Spectroscopy to Quantify Bulk Breast Tissue Properties in Girls Age 10 - 14 Years
The period between menarche and the age of first full-term pregnancy has been identified as
being most crucial for establishing an individual's future breast cancer risk.
Epidemiological studies further suggest exposures, such as foods and toxins, during
adolescence to have a significant impact on the likelihood of transformation in the
developing breast resulting in cancer later in life. Adolescent diet affects mammary
development directly and indirectly by influencing the micronutrients and the hormonal
status of the adolescent. The goal of this study is to investigate the feasibility of
Optical Spectroscopy (OS), a method based on differential light scattering and absorption in
tissue, to quantify bulk breast tissue properties in adolescent females.
Observational Model: Cohort, Time Perspective: Cross-Sectional
Lothar Lilge, PhD
Ontario Cancer Institute, University Health Network, Toronto, Ontario, Canada M5G 2M9; Department of Biophysics and Bioimaging, University of Toronto, Toronto, Ontario, Canada M5G 2M9
Canada: Health Canada