Exploratory Study on FDG-PET Scanning in Evaluating the Metabolic Activity of Liver Metastases Before and After Resection of the Primary Tumor in Patients With a Colorectal Malignancy
18 Years
N/A
Both
Colorectal Neoplasms
Trial Information
Exploratory Study on FDG-PET Scanning in Evaluating the Metabolic Activity of Liver Metastases Before and After Resection of the Primary Tumor in Patients With a Colorectal Malignancy
The goal of this study is to evaluate the activity of liver metastases before and after
resection of the primary tumor. Non-invasive assessment of tumor metabolism is possible in
vivo by means of positron emission tomography (PET)-scanning. Therefore, FDG-PET scan offers
a suitable approach to determine the influence of removal of a primary colorectal tumor on
metabolic activity of the liver metastases. The FDG uptake in the liver metastases is
quantified by calculating standardised uptake values (SUVs).
Inclusion Criteria:
- Colorectal cancer and synchronous liver metastases
Exclusion Criteria:
- Pregnancy
Type of Study:
Interventional
Study Design:
Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic
Outcome Measure:
Increase in metabolic activity of liver metastases after resection of the primary tumor compared to the activity of metastases in patients without primary tumor resection
Principal Investigator
Theo Ruers, PhD
Investigator Role:
Principal Investigator
Investigator Affiliation:
Radboud University
Authority:
Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)
Study ID:
CP 2005
NCT ID:
NCT00184782
Start Date:
September 2003
Completion Date:
December 2008
Related Keywords:
- Colorectal Neoplasms
- colorectal cancer
- liver metastases
- metabolic activity
- Neoplasms
- Colorectal Neoplasms
- Neoplasm Metastasis
- Liver Neoplasms
Name | Location |
|---|
