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Evaluation of Immunoregulatory Cells in Hematopoietic Stem Cell Transplant (HSCT)


N/A
18 Years
70 Years
Not Enrolling
Both
Hematopoietic Stem Cell Transplantation, Graft vs Host Disease

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Trial Information

Evaluation of Immunoregulatory Cells in Hematopoietic Stem Cell Transplant (HSCT)


The investigators' hypothesis is that the graft-versus-tumor effect can be enhanced while
minimizing the complications of graft-versus-host disease (GVHD) by determining the
qualitative and quantitative changes in T regulatory cells throughout the transplant
process. Their understanding of this can lead to new treatment strategies and improved
clinical therapeutic implications.


Inclusion Criteria:



- Patients 18-70 years old undergoing either autologous transplant or allogeneic
transplant for various hematologic conditions

Exclusion Criteria:

- Patients < 18 or > 70 years old undergoing either autologous transplant or allogeneic
transplant

Type of Study:

Observational

Study Design:

Observational Model: Case-Only, Time Perspective: Prospective

Principal Investigator

Adetola A Kassim, M.D.

Investigator Role:

Principal Investigator

Investigator Affiliation:

Vanderbilt University

Authority:

United States: Institutional Review Board

Study ID:

BMT 030261

NCT ID:

NCT00179049

Start Date:

April 2003

Completion Date:

April 2008

Related Keywords:

  • Hematopoietic Stem Cell Transplantation
  • Graft Vs Host Disease
  • T-Lymphocyte Subsets
  • Graft vs Host Disease

Name

Location
Vanderbilt University Medical Center Nashville, Tennessee  37232-2516