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Radiation-Induced Cytokine Cascades and Their Correlation With Central Nervous System Injury


N/A
N/A
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Open (Enrolling)
Both
Brain Neoplasm

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Trial Information

Radiation-Induced Cytokine Cascades and Their Correlation With Central Nervous System Injury


Inclusion Criteria:



- Any patient who will be treated to the brain or spinal axis for a CNS tum Patients so
treated will be stratified according to whether or not the hypo is included in the
treatment fields.

- Patients receiving external beam radiation to the brain may also be rece
chemotherapy or interferon-beta. (Add. #1, 11-9-95)

- Patients receiving high dose rate (stereotactic radiosurgery) are eligible.

- Patients must sign a study specific informed consent meeting all federal a
guidelines.

- Patients of any age, including children, are eligible (Add. #3, 11/25/97).

Exclusion Criteria:

- Patients who have a malignancy involving the hypothalamic-pituitary ax

- Patients who are not treated with irradiation to the brain or spinal axis.

Type of Study:

Observational

Study Design:

Observational Model: Cohort, Time Perspective: Prospective

Principal Investigator

Louis S Constine, MD

Investigator Role:

Study Chair

Investigator Affiliation:

Universtiy of Rochester, Dept of Radiation Oncology

Authority:

United States: Institutional Review Board

Study ID:

URCC 11095

NCT ID:

NCT00178295

Start Date:

November 1999

Completion Date:

Related Keywords:

  • Brain Neoplasm
  • Brain Neoplasms
  • Neoplasms
  • Trauma, Nervous System

Name

Location

University of Rochester, Dept. Radiation OncologyRochester, New York  14642