Know Cancer

or
forgot password

To Evaluate the Effects of Transfer of Submandibular Salivary Gland to the Submental Region (Outside the Radiation Field) on Xerostomia in Head and Neck Cancer Patients Receiving Radiation as the Primary Treatment Versus Patients Who Will Not Have Such a Procedure


Phase 2
18 Years
N/A
Not Enrolling
Both
Head and Neck Cancer

Thank you

Trial Information

To Evaluate the Effects of Transfer of Submandibular Salivary Gland to the Submental Region (Outside the Radiation Field) on Xerostomia in Head and Neck Cancer Patients Receiving Radiation as the Primary Treatment Versus Patients Who Will Not Have Such a Procedure


Inclusion Criteria:



- Patients with a histological diagnosis of squamous cell carcinoma

- Patients with unilateral or no neck involvement of the nasopharynx

- The submandibular transfer will be done on the uninvolved side of the neck.

- Karnofsky score greater than or equal to 70

- Expected survival greater than one year

- A signed informed consent

Exclusion Criteria:

- Bilateral neck nodes involvement. Involvement of level 1 lymph nodes on the side of
the proposed procedure.

Type of Study:

Interventional

Study Design:

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention

Outcome Measure:

Quality of life

Principal Investigator

Naresh Jha, MBBA

Investigator Role:

Principal Investigator

Investigator Affiliation:

Alberta Health Services

Authority:

Canada: Ethics Review Committee

Study ID:

16620

NCT ID:

NCT00168116

Start Date:

July 2000

Completion Date:

June 2009

Related Keywords:

  • Head and Neck Cancer
  • nasopharynx
  • xerostomia
  • prevention
  • Head and Neck Neoplasms
  • Xerostomia

Name

Location