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Mindfulness Meditation in Bone Marrow Transplantation

Phase 2/Phase 3
21 Years
Not Enrolling
Hematologic Malignancy, Bone Marrow Transplantation, Stem Cell Transplantation

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Trial Information

Mindfulness Meditation in Bone Marrow Transplantation

Patients will be assigned to one of three study groups:

1. receives the normal standard care;

2. meets with an oncology nurse educator, in addition to the regular nurses on the
transplant team. The nurse educator will provide information and answers to patient's
questions about the stem cell/bone marrow transplant experience; or

3. is taught mindfulness meditation by a nurse who is trained to be a mindfulness
instructor and by an audio CD.

Mindfulness meditation is a technique that may help in coping with the stress and
difficulties associated with cancer and undergoing a stem cell/bone marrow transplant. It
involves learning to be in the present moment by paying attention to your breathing, sights,
and sounds, and to sensations you may be experiencing, or thoughts and feelings you may be

Mindfulness meditation has been shown to be helpful to patients in the clinic who have
cancer and other medical conditions.

Patients, regardless of random group assignment, will complete a questionnaire 8 different
times, from before they are admitted to the hospital until 6 months after discharge.

Patients will also provide two urine samples while in the hospital to measure the levels of
stress hormones present in the urine.

Inclusion Criteria:

- Autologous stem cell transplantation for hematologic malignancy

- First transplant

- 21 years of age or older

- Speaks and understands English

Exclusion Criteria:

- Planned tandem (more than one) transplant

- Taking corticosteroids on a regular basis for a chronic condition

- Prior formal mindfulness meditation training

- Significant cognitive impairment and/or confirmed psychosis or thought disorder

Type of Study:


Study Design:

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label

Outcome Measure:

Psychological functioning

Outcome Time Frame:

1 year

Safety Issue:


Principal Investigator

Susan Bauer-Wu, PhD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Emory University


United States: Institutional Review Board

Study ID:




Start Date:

April 2005

Completion Date:

June 2011

Related Keywords:

  • Hematologic Malignancy
  • Bone Marrow Transplantation
  • Stem Cell Transplantation
  • Meditation
  • Mindfulness meditation
  • Bone Marrow Transplant
  • Stem Cell Transplant
  • Neoplasms
  • Hematologic Neoplasms



Dana-Farber Cancer Institute Boston, Massachusetts  02115
Emory University Atlanta, Georgia  30322
University of Massachusetts Medical School Worcester, Massachusetts  01605