Inclusion Criteria:

- Patients must have a diagnosis of non-B-cell, non-Hodgkin's lymphoma (including
T-cell, null-cell, or NK-cell lymphoma, but excluding lymphoblastic lymphoma)

- Stage II, III, or IV disease requiring chemotherapy

- At least one site of measurable disease, 1.5 cm in diameter or greater

- Age > or = 18 years

- Absolute granulocyte count of at least 1500 cells/mm3, unless neutropenia is due to
marrow infiltration by the tumor

- Platelet count of at least 100,000 cells/mm3 unless thrombocytopenia is due to marrow
infiltration by tumor

- Creatinine less than 2 x upper limits of normal (ULN)

- Total bilirubin less than 2 x ULN (dose reduced vincristine and adriamycin required
for bilirubin > 1.2 mg/dL)

- Echocardiogram (Echo) or multiple gate acquisition scan (MUGA) documenting a normal
ejection fraction prior to chemotherapy

- Able to give informed consent

Exclusion Criteria:

- Known central nervous system (CNS) involvement

- Known HIV disease

- Patients who are pregnant or nursing

- Any factor which might limit the patient's ability to provide informed consent

- Life expectancy < 3 months

- Patients who are unwilling to agree to use an effective means of birth control while
on treatment