Trial Information
Development of a Prostate Deformation Model to Enable Accurate Registration of Endorectal Coil Magnetic Resonance Images (ERC-MRI) to Reference Treatment Planning CT Images
Inclusion Criteria:
- adenocarcinoma of the prostate
- patient undergoing dose escalated conformal EBRT
- low or intermediate risk prognostic factors: PSA < or equa to20, gleason score <8,
T
- > or equal to 18 years of age
- ECOG performance status 0 or 1
Exclusion Criteria:
- contraindications to MRI
- bleeding diathesis and anti-coagulative therapy that cannot be temporarily ceased
precluding insertion of fiducial markers
- IFB or collagen vascular disease
- previous colorectal surgery
- previous pelvic RT
Type of Study:
Interventional
Study Design:
Allocation: Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Prevention
Outcome Measure:
The primary aim of this study is to develop a prostate deformation model using the finite element method from anatomic MR images of the prostate gland acquired with and without ERC.
Principal Investigator
Menard Cynthia, MD
Investigator Role:
Principal Investigator
Investigator Affiliation:
Princess Margaret Hospital, Canada
Authority:
Canada: Ethics Review Committee
Study ID:
UHN REB 05-0041-C
NCT ID:
NCT00160953
Start Date:
February 2005
Completion Date:
February 2010
Related Keywords:
- Prostatic Neoplasms
- Neoplasms
- Prostatic Neoplasms