Trial Information
Ultrasound Guided Interstitial Laser Photocoagulation on Benign Thyroid Nodules
Inclusion Criteria:
- Patients with a solitary solid thyroid nodule confirmed by ultrasonography
- Patients with a solitary cystadenoma (cystic part more than 2 mL) confirmed by
ultrasonography
- Patients with an autonomous functioning thyroid nodule.
Exclusion Criteria:
- No family history of thyroid cancer
- Prior radiation towards the neck
- Fine needle biopsy without valid diagnostic criteria for benign thyroid disease
- Nodules larger than 4 cm (largest diameter)
- Suspicion of malignancy
- Increased serum calcitonin
- Pregnancy or lactation
- Alcohol, medicine or drug abuse
- No safe contraception
- Physical or psychic condition that hinders corporation
Type of Study:
Interventional
Study Design:
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Outcome Measure:
To evaluate the efficacy and feasibility repeated ILP treatments in a prospective randomised study where the nodule and thyroid volume are measured 1, 3, 6 and 12 months after the ILP.
Principal Investigator
Helle Døssing, MD
Investigator Role:
Principal Investigator
Investigator Affiliation:
Odense University Hospital
Authority:
Denmark: National Board of Health
Study ID:
017
NCT ID:
NCT00150150
Start Date:
January 2001
Completion Date:
March 2006
Related Keywords:
- Benign Solitary Solid
- Cystic Thyroid Nodules
- Interventional ultrasound
- interstitial laser theraphy
- tumor ablation
- nodule reduction
- adverse effects
- patient satesfaction
- Thyroid Diseases
- Thyroid Nodule