Randomized Controlled Trial to Evaluate Surgical Approaches to Gastric Cancer Invading the Esophagus (JCOG9502)
For gastric cancers with esophageal invasion (Siewert type II and III), thoraco-abdominal
approach has shown better survival results than abdominal approach in retrospective
analyses. However, patients having mediastinal nodal metastasis have poor prognosis and the
benefit of thoraco-abdominal approach is still controversial. We evaluated the two
approaches in a prospective randomized trial.
Interventional
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
overall survival
Mitsuru Sasako, MD
Study Chair
Gastric Surgery Division, National Cancer Center Hospital
Japan: Ministry of Health, Labor and Welfare
JCOG9502
NCT00149266
July 1995
December 2008
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