Randomized Controlled Trial to Evaluate Laparoscopic Versus Open Surgery for Colorectal Cancer（JCOG 0404,CRC Surg-LAP/OPEN)
The benefits of laparoscopic surgery (LAP) in comparison to open surgery (OPEN) have been
suggested with respect to decreased morbidity, decreased pain, faster recovery, and shorter
hospital stay.1-4 However, the long-term survival of LAP for colorectal cancer is still
unclear, especially for advanced colorectal cancer requiring extended lymphadenectomy.
Thus, the investigators designed a study which investigates whether LAP is suitable for
advanced colorectal cancer with respect to survival and post-operative morbidity.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
During the study conduct
Seigo Kitano, MD, PhD,FACS
Japan: Ministry of Health, Labor and Welfare