The Incidence of Adjacent Synchronous Ipsilateral Infiltrating Carcinoma, DCIS, or Atypical Ductal Hyperplasia (ADH) in Patients Diagnosed With Lobular Neoplasia of the Breast by Core Needle Biopsy
Patients will undergo a breast biopsy at which the area found to be ALH or LCIS on core
biopsy will be removed surgically through a small incision in the breast.
- The surgical biopsy specimen will be carefully examined by a pathologist, and may be
useful in guiding further therapy if needed.
- In the future, tissue from the surgical biopsy may be used to study genetic changes
that may be responsible for cancer formation and prevention. The tissue will be kept
for future research for up to 10 years.
Observational Model: Case-Only, Time Perspective: Prospective
Rate of upstaging from Lobular Neoplasia on core biopsy to invasive breast cancer or ductal carcinoma in situ on excisional biopsy
Faina Nakhlis, MD
Dana-Farber Cancer Institute
United States: Institutional Review Board
|Beth Israel Deaconess Medical Center||Boston, Massachusetts 02215|
|Dana-Farber Cancer Center||Boston, Massachusetts 02115|