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Conditioning Regimens for Patients With Severe Aplastic Anemia Transplanted With Marrow From an Unrelated Donor


Phase 1/Phase 2
N/A
55 Years
Not Enrolling
Both
Anemia, Aplastic

Thank you

Trial Information

Conditioning Regimens for Patients With Severe Aplastic Anemia Transplanted With Marrow From an Unrelated Donor


Inclusion Criteria:



- Life-threatening marrow failure of nonmalignant etiology;

- failure to respond to the best available immunosuppressive treatment;

- lack of a HLA-identical family member

Exclusion Criteria:

- Severe disease other than aplastic anemia that would severly limit the probability of
survival during the graft procedure;

- HIV seropositive patients;

- clonal abnormalities or myelodysplastic syndrome;

Type of Study:

Interventional

Study Design:

Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Outcome Measure:

Sustained engraftment; survival

Principal Investigator

Joachim Deeg, M.D.

Investigator Role:

Principal Investigator

Investigator Affiliation:

Fred Hutchinson Cancer Research Center

Authority:

United States: Institutional Review Board

Study ID:

FHCRC 0800.01

NCT ID:

NCT00144729

Start Date:

May 1993

Completion Date:

July 2007

Related Keywords:

  • Anemia, Aplastic
  • Anemia
  • Anemia, Aplastic

Name

Location

Fred Hutchinson Cancer Research Center/Seattle Cancer Care AllianceSeattle, Washington  98109