Trial Information
Conditioning Regimens for Patients With Severe Aplastic Anemia Transplanted With Marrow From an Unrelated Donor
Inclusion Criteria:
- Life-threatening marrow failure of nonmalignant etiology;
- failure to respond to the best available immunosuppressive treatment;
- lack of a HLA-identical family member
Exclusion Criteria:
- Severe disease other than aplastic anemia that would severly limit the probability of
survival during the graft procedure;
- HIV seropositive patients;
- clonal abnormalities or myelodysplastic syndrome;
Type of Study:
Interventional
Study Design:
Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Outcome Measure:
Sustained engraftment; survival
Principal Investigator
Joachim Deeg, M.D.
Investigator Role:
Principal Investigator
Investigator Affiliation:
Fred Hutchinson Cancer Research Center
Authority:
United States: Institutional Review Board
Study ID:
FHCRC 0800.01
NCT ID:
NCT00144729
Start Date:
May 1993
Completion Date:
July 2007
Related Keywords:
- Anemia, Aplastic
- Anemia
- Anemia, Aplastic
Name | Location |
Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance |
Seattle, Washington 98109 |