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Angiogenic Profile and Non-invasive Imaging May Predict Tumor Progression of High Risk Group Low Grade Glioma (LGG)


N/A
18 Years
N/A
Not Enrolling
Both
Glioma

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Trial Information

Angiogenic Profile and Non-invasive Imaging May Predict Tumor Progression of High Risk Group Low Grade Glioma (LGG)


Summary: Comprehensive analysis of the angiogenesis-related gene expression profiles and
tumor perfusion of patients with LGG will provide a novel understanding of subgroup (low and
high-risk) of LGG. Thus, this study will allow identifying clinically relevant factors
predictive for tumor progression and to select patients in high-risk group for adjuvant
radiation therapy.


Inclusion Criteria:



- Greater than 18 years of age

- Brain tumor with no contrast enhancement on conventional MRI and confirmed
histological of LGG

- No adjustment treatment

- Consent to participate in study

- No contra-indication for dynamic contrast-enhanced (DCE)-MRI

Type of Study:

Observational

Study Design:

Observational Model: Case-Only, Time Perspective: Prospective

Principal Investigator

Bassam Abdulkarim, MD

Investigator Role:

Principal Investigator

Investigator Affiliation:

Alberta Health Services

Authority:

Canada: Health Canada

Study ID:

CNS-09-0024/ethics 21656

NCT ID:

NCT00137488

Start Date:

November 2005

Completion Date:

Related Keywords:

  • Glioma
  • non-enhancing lesion
  • low grade glioma
  • high risk group selection
  • Glioma

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