Know Cancer

or
forgot password

A Phase III Randomized, Open-Label Study of Docetaxel in Combination With CG1940 and CG8711 Versus Docetaxel and Prednisone in Taxane-Naïve Patients With Metastatic Hormone-Refractory Prostate Cancer With Pain


Phase 3
18 Years
N/A
Not Enrolling
Male
Prostate Cancer

Thank you

Trial Information

A Phase III Randomized, Open-Label Study of Docetaxel in Combination With CG1940 and CG8711 Versus Docetaxel and Prednisone in Taxane-Naïve Patients With Metastatic Hormone-Refractory Prostate Cancer With Pain


Inclusion Criteria:



- Confirmed diagnosis of or clinical history consistent with adenocarcinoma of the
prostate

- Metastatic prostate cancer deemed to be unresponsive or refractory to hormone therapy

- Detectable metastases

- ECOG performance status ≤2 (Performance status of 3 if due to bone pain)

- Any Gleason score

- Only one prior treatment with systemic chemotherapy

- No prior treatment with gene therapy

- No prior immunotherapy for prostate cancer

- Taxane naïve

- Experiencing cancer-related pain

Type of Study:

Interventional

Study Design:

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Outcome Measure:

Survival

Safety Issue:

No

Authority:

United States: Food and Drug Administration

Study ID:

G-0034

NCT ID:

NCT00133224

Start Date:

July 2005

Completion Date:

June 2009

Related Keywords:

  • Prostate Cancer
  • Advanced Prostate Cancer
  • HRPC
  • Prostate
  • Cancer
  • Metastatic
  • Hormone-refractory
  • GVAX
  • Chemotherapy
  • Taxotere
  • Docetaxel
  • Prednisone
  • Vaccine
  • Allogeneic cells
  • Prostatic Neoplasms

Name

Location

Mayo Clinic - JacksonvilleJacksonville, Florida  32224
James Graham Brown Cancer CenterLouisville, Kentucky  40202
Hackensack University Medical CenterHackensack, New Jersey  07601
Cancer Centers of the CarolinasGreenville, South Carolina  29605
Frederick Memorial Hospital Regional Cancer Therapy CenterFrederick, Maryland  21701
Mary Crowley Medical Research CenterDallas, Texas  75246
San Bernardino Urology AssociatesSan Bernardino, California  92404
Lakeland Regional Cancer CenterLakeland, Florida  33805
Providence Portland Medical CenterPortland, Oregon  97213-3635
California Pacific Medical CenterSan Francisco, California  94115
Atlanta Va Medical CenterDecatur, Georgia  30033
Sharp HealthcareSan Diego, California  92121
Gabrail Cancer CenterCanton, Ohio  44718
Hematology Oncology Associates of the Treasure CoastPort St. Lucie, Florida  34952
The West ClinicMemphis, Tennessee  38120
Center for Oncology Research & Treatment, PADallas, Texas  75230
Presbyterian Hospital Center for Cancer ResearchCharlotte, North Carolina  28204
Dallas Oncology ConsultantsDallas, Texas  75201
Alaska Clinical Research CenterAnchorage, Alaska  99508
Nevada Cancer InstituteLas Vegas, Nevada  89135
Loma Linda UniversityLoma Linda, California  92354
Billings ClinicBillings, Montana  59107-7000
Cancer Research & Prevention CenterSoquel, California  95073
Mobley Research CenterHouston, Texas  77024
Desert Hematology Oncology Medical GroupRancho Mirage, California  92270
Urology San Antonio Research, PASan Antonio, Texas  78229
NYU Clinical Cancer CenterNew York, New York  10016
St. Edward Mercy Medical CenterFort Smith, Arkansas  72917
Onocology Care Medical AssociatesLos Angeles, California  90057
Kaiser Permanente Medical Group Dept. of Oncology ResearchSan Diego, California  92120
UCSF Mt. Zion Cancer CenterSan Francisco, California  94115
Cancer Center and Department of MedicineAurora, Colorado  80010
Jupiter Hematology & Oncology AssociatesJupiter, Florida  33458
Peachtree Hematology & Oncology Consultants, PCAtlanta, Georgia  30309
Emory Winship Cancer InstituteAtlanta, Georgia  30322
Medical & Surgical SpecialistsGalesburg, Illinois  61401
General Clinical Research Center University of MichiganAnn Arbor, Michigan  48109
Hematology & Oncology Consultants P.C.Omaha, Nebraska  68122
New Mexico OncologyAlbuquerque, New Mexico  87109
North Shore Hematology Oncology Associates P.C.East Setauket, New York  11733
Kaiser Permanente Oncology/HematologyPortland, Oregon  97227
Northwest Cancer CenterHouston, Texas  77042
Seattle Cancer Care Alliance, Univ. of WashingtonSeattle, Washington  98109