Inclusion Criteria

Inclusion Criteria

- Newly diagnosed prostate cancer

- Has completed conventional staging examinations, including biopsy with Gleason score,
CT scan of the abdomen and pelvis, and whole-body bone scintigraphy AND conventional
staging examinations negative

- Candidate for curative radical prostatectomy OR curative radiotherapy OR staging
lymphadenectomy prior to surgery

- Deemed to be at medium or high risk for recurrence after initial curative treatment,
as defined by 1 of the following criteria:

- Gleason score 7 AND prostate-specific antigen (PSA) 10-20 ng/mL

- Gleason score ≥ 8 AND PSA < 10 ng/mL

- Gleason score ≥ 8 AND PSA > 10 ng/mL

- Any Gleason score AND PSA > 20 ng/mL

Exclusion Therapy:

- Not a candidate for treatment by surgery or radiation therapy with curative intent

- Inability to give informed consent

- Patients with other invasive malignancies, with the exception of non-melanoma skin
cancer, who had (or have) any evidence of other cancer present within the last 5
years