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Reducing Obesity at the Workplace: a Randomized Trial

18 Years
70 Years
Not Enrolling
Obesity, Cardiovascular Diseases, Heart Diseases

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Trial Information

Reducing Obesity at the Workplace: a Randomized Trial


More than half of American adults are overweight or obese, and this proportion is
increasing. The health risks associated with obesity include diabetes, cardiovascular
disease, arthritis, and some cancers. It is well established that on an individual level,
weight gain is caused by taking in more calories than are expended. On a population basis,
the prevalence of overweight and obesity is associated with a myriad of influences,
including genetic and physiological factors as well as social, behavioral, cultural, and
environmental factors. Behavioral factors that contribute to weight gain include eating
choices that lead to increased energy intake and physical activity choices that lead to
decreased energy expenditure. For a majority of overweight individuals, restoring the
balance between energy intake and expenditure is difficult.


This study will develop and test a comprehensive intervention involving simple messages that
will integrate changes in dietary intake with changes in energy expenditure, while
simultaneously modifying structural and environmental factors to promote social support and
opportunities for behavioral change. The study will recruit and randomize 48 worksites to a
2-year intervention in which the following will be carried out: build a physical activity
intervention combining increased daily physical activity and regular, structured exercise;
build a dietary intervention that will promote lower calorie intake; and increase worksite
access to both healthy foods and physical activity. The primary aim is to evaluate the
effectiveness of the intervention in reducing or maintaining body mass index in a randomized
controlled trial of worksites. The study will compare changes in body mass index in
intervention versus control worksites using two cross-sectional surveys at baseline and
follow-up. Additional assessments using biomarkers and fitness measures will be performed
in a subset of employees. The research team has considerable experience with interventions
at the worksite level and substantial expertise in obesity prevention.

Inclusion Criteria

The study is enrolling employees only at participating worksites.


- Meets specific standard industrial codes

- At least 20% of employees are sedentary

- Willing to provide a list of employees

- Able to achieve at least a 70% response rate to the baseline survey

Type of Study:


Study Design:

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Prevention

Outcome Measure:

Body mass index

Outcome Time Frame:

Measured at Month 24 follow-up visit; adjusted for baseline body mass index

Safety Issue:


Principal Investigator

Shirley Beresford

Investigator Role:

Study Chair

Investigator Affiliation:

Fred Hutchinson Cancer Research Center


United States: Federal Government

Study ID:




Start Date:

September 2004

Completion Date:

November 2009

Related Keywords:

  • Obesity
  • Cardiovascular Diseases
  • Heart Diseases
  • Cardiovascular Diseases
  • Heart Diseases
  • Obesity



Fred Hutchinson Cancer Research Center Seattle, Washington  98109