Inclusion Criteria:

- Women who report elevated fatigue following cancer diagnosis and treatment

Exclusion Criteria:

- Women who have medical conditions that may affect the immune system or are associated
with baseline fatigue syndrome, and/or who use medications that affect the immune
system or fatigue.

- Women with major affective disorders and those with sleep or pain disorders.

- Presence of medical conditions that may but subject at undue risk for experimental
procedures.

- Chronic or recurring infections, symptoms of chronic heart failure, demyelinating
disorders, and those taking immunosuppressive medications.

- Neoplastic disease other than primary breast cancer

- Compromised cardiovascular function

- Insulin-dependent diabetes

- Neurological disorder

- Peripheral neuropathy

- Pregnancy

- Use of psychotropic medications within 2 weeks of screening

- Abnormal screening laboratory findings (i.e., creatinine > 1.4mg%; anemia; abnormal
thyroid hormone; hematuria; elevated liver function tests, low protein or albumin;
fasting glucose >120mg%; elevated FTI or TSH; positive TB screening, HIV screening or
hepatitis C).

- Smokers