Does Blocking Proinflammatory Cytokines Diminish Cancer-Related Fatigue?
- Determine the association between the body's immune system and energy, sleep, mood, and
other symptoms in postmenopausal women who have undergone treatment for stage 0-II
- Determine whether treatment with infliximab affects energy and immune function in these
OUTLINE: Patients receive infliximab IV over 2 hours.
Patients complete a diary twice daily for 14 days before and for 14 days after infliximab
administration to assess fatigue and other symptoms, including mood, pain, and sleep.
After completion of study treatment, patients are followed at 2 weeks and then monthly for 3
PROJECTED ACCRUAL: A total of 10 patients will be accrued for this study.
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Supportive Care
Fatigue as measured by the fatigue symptom inventory (FSI) at baseline and after completion of study treatment
Patricia A. Ganz, MD
Jonsson Comprehensive Cancer Center
United States: Food and Drug Administration
|Jonsson Comprehensive Cancer Center at UCLA||Los Angeles, California 90095-1781|