Metabolic Adaptations to Six Month Caloric Restriction
This study tests whether chronic caloric restriction improves risk factors of longevity in
humans as it is known to do in animals, by measuring a variety of factors dealing with
metabolism and oxidative stress, through physical evaluations and laboratory tests.
Participants will receive dietary counseling and free medical evaluations. In addition,
each volunteer will be asked to do one of the following:
1. Follow a reduced calorie diet
2. Follow a reduced calorie diet using a liquid diet
3. Increase physical activity while on a reduced calorie diet
4. Follow a standard diet.
Three separate five-day inpatient stays are required.
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind, Primary Purpose: Prevention
Eric Ravussin, Ph.D.
Pennington Biomedical Research Center
United States: Federal Government
|Pennington Biomedical Research Center, 6400 Perkins Road||Baton Rouge, Louisiana 70808|