Stress-Immune Response and Cervical Cancer
- Compare quality of life (QOL) at baseline and changes in QOL, immune response, and
neuroendocrine parameters over time in patients who have completed treatment for stage
I-III cervical cancer receiving psychosocial telephone counseling vs usual care.
- Correlate psychosocial measures with immunologic stance.
OUTLINE: This is a randomized, controlled, parallel-group study. Patients are randomized to
1 of 2 intervention arms.
- Arm I: Patients undergo psychosocial telephone counseling comprising 5 weekly sessions
and a 1-month follow-up session to learn strategies for reducing stress.
- Arm II: Patients undergo usual care for approximately 4 months. All patients complete
questionnaires and Quality of life assessment at baseline and at 4 months. They also
undergo saliva and blood sample collections at baseline and at 4 months for neuroimmune
PROJECTED ACCRUAL: A total of 50 patients will be accrued for this study.
Quality of life
Lari B. Wenzel, PhD
Chao Family Comprehensive Cancer Center
United States: Federal Government
|UCI, Health Policy and Research Center||Irvine, California 92697|