Inclusion Criteria

Inclusion criteria

- Medical diagnosis of CTCL, and positivity for the CD4 receptor.

- Late stage CTCL.

- Have received at least one prior anti-cancer therapy with inadequate effect.

- WHO performance status 0,1 or 2

- Male or female, age 18 or older.

- Signed informed consent.

Exclusion Criteria

- Certain rare types of CTCL.

- Previous treatment with other anti-CD4 medications.

- More than two previous treatments with systemic chemotherapy.

- Certain anti-psoriasis or anti-cancer therapies within the last 4 weeks before
entering this trial.

- Some types of steroid treatments less than two weeks before entering the trial.

- Prolonged exposure to sunlight or UV light during the trial.

- Other cancer diseases, except certain skin cancers or cervix cancer.

- Chronic infectious disease requiring medication.

- Certain serious medical conditions, including kidney or liver disease, some
psychiatric illnesses, and stomach, lung, heart, hormonal, nerve or blood diseases.

- Certain laboratory values which are too high or too low.

- HIV positivity.

- Pregnant or breast-feeding women.

- Women of childbearing age who are unable or unwilling to use an IUD or hormonal birth
control during the whole trial.

- If you are participating in another trial with a different new drug 4 weeks before
you enter this trial.