Inclusion Criteria

- INCLUSION CRITERIA:

The subject carries the diagnosis of malignant solid tumor or a malignant or non-malignant
hematologic disorder, and is being screened at the NIH for eligibility for an NIH Clinical
Center treatment protocol.

OR

The subject carries the diagnosis of malignant solid tumor or a malignant or non-malignant
hematologic disorder, and is already enrolled on a clinical protocol at the NIH Clinical
Center.

OR

The subject is a related HLA-compatible family member of a patient (bearing a diagnosis of
malignant solid tumor or a malignant or non-malignant hematologic) being evaluated for or
already enrolled on a clinical protocol at the NIH Clinical Center and is identified as a
potentially suitable donor of allogeneic hematopoietic stem cells for transplantation.

OR

The subject carries the diagnosis of malignant solid tumor or a malignant or non malignant
hematologic disorder or a bone marrow failure condition and is not available to
participate in an NIH Clinical Center treatment protocol, or travel to the NIH clinical
center, but is referred for participation through their home health care provider.

The subject or the subject's guardian is able to understand the investigational nature of
the study and provide informed consent after initial counseling by clinical staff.
Separate consent forms for all interventional or surgical procedures will be obtained
after explanation of the specific procedure.

Age 2 years and older (no upper limit)

EXCLUSION CRITERIA:

Subjects unable to comprehend the investigational nature of the procedure

Age less than 2 years