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Development and Evaluation of Techniques for Computer Aided Detection and Diagnosis From Radiologic Images


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Open (Enrolling)
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Diagnostic Imaging

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Trial Information

Development and Evaluation of Techniques for Computer Aided Detection and Diagnosis From Radiologic Images


Radiologic images are becoming more and more complex, and utilization of radiologic
techniques is accelerating. Radiologists and other clinicians are being inundated with
radiologic data. Computer aided detection and diagnosis (CAD) have the potential to improve
patient care by increasing sensitivity of diagnostic tests, reducing false positives and
improving physician efficiency. Computer aided detection and diagnosis have been under
development for many years yet there is still much work to be done to move it from the bench
to the bedside. The purpose of this project is to develop and evaluate techniques for CAD
using the existing radiologic data available in the Clinical Center's Department of
Diagnostic Radiology. Such techniques include but are not limited to automated detection of
melanoma, bone metastases and pulmonary emboli, colonic polyps and abdominal tumors, and
abnormal morphology of organs. The outcome of this study will be algorithms and software
that accurately detect and characterize lesions, model anatomy and monitor diseases on
radiologic studies.

Inclusion Criteria


- INCLUSION CRITERIA:

Inclusion criteria are the availability of radiologic examinations in the clinical PACS
(picture archiving system) in the Clinical Center. Existing Patient scans with and without
the target lesion will be included. Examples of target lesions include subcutaneous and
bone lesions and pulmonary emboli, although patient scans with other disorders depicted on
radiologic studies may be included when appropriate. Patient scans without the target
lesion may be included to determine the specificity of the computer aided detection or
diagnosis algorithm.

EXCLUSION CRITERIA:

There are no exclusion criteria.

Type of Study:

Observational

Study Design:

N/A

Principal Investigator

Ronald M Summers, M.D.

Investigator Role:

Principal Investigator

Investigator Affiliation:

National Institutes of Health Clinical Center (CC)

Authority:

United States: Federal Government

Study ID:

030128

NCT ID:

NCT00057252

Start Date:

March 2003

Completion Date:

Related Keywords:

  • Diagnostic Imaging
  • Diagnostic
  • Imaging
  • Healthy Volunteer
  • HV

Name

Location

National Institutes of Health Clinical Center, 9000 Rockville PikeBethesda, Maryland  20892