Primary Purpose: Treatment
Dose Limiting Toxicities (DLTs)
DLT is defined as experiencing Common Toxicity Criteria (CTC) grade 3 or 4 headache with onset within 24 h of receiving ZD4054, CTC grade 2 rhinitis leading to the withdrawal of the subject, or other CTC grade 3 or 4 toxicity that was considered to be related to ZD4054 treatment. The numbers of patients with a DLT are reported.
Baseline to Day 29.
United States: Food and Drug Administration
|Research Site||Akron, Ohio|
|Research Site||Appleton, Wisconsin|