Trial Information

Vaginal Length, Elasticity, Lubrication And Sexual Function In Women With Stage IB2 Cervix Carcinoma

OBJECTIVES:

- Obtain estimates of changes in vaginal length, perceived vaginal elasticity, perceived
vaginal lubrication, and sexual activity, response, and satisfaction among patients
with stage IB2 cervical cancer.

- Compare these differences between the patients in the two treatment groups in GOG-0201.

- Determine the relationships between vaginal dilation activities and vaginal length
changes in these patients.

- Determine the association between smoking and vaginal length and between smoking and
vaginal dryness in these patients after therapy for cervical cancer.

- Assess the extent of subject interest in and preferred methods of sexual counseling
related to problems resulting from treatment in these patients.

OUTLINE: Vaginal length is measured using Vaginal Sound, a modified plastic vaginal dilator.
The data about vaginal elasticity and lubrication and sexual activity, response, and
satisfaction are obtained from patient self-report, as well as vaginal dilation activities.
Measurement and assessments are taken before treatment and then at 3, 6, 12, and 24 months.

Patients are followed every 3 months for 2 years.

PROJECTED ACCRUAL: Approximately 150 patients will be accrued for this study.