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A Double-Blind Study Of Nutritional Intervention For The Treatment Of Cancer Cachexia Using Juven® Nutritional Supplement


Phase 3
17 Years
N/A
Not Enrolling
Both
Cachexia, Lymphoma, Lymphoproliferative Disorder, Unspecified Adult Solid Tumor, Protocol Specific

Thank you

Trial Information

A Double-Blind Study Of Nutritional Intervention For The Treatment Of Cancer Cachexia Using Juven® Nutritional Supplement


OBJECTIVES:

- Compare the change in lean body mass of patients treated with Juven® vs a non-Juven®
supplement.

- Compare the change in fatigue and quality of life of patients treated with these
supplements.

- Compare the results of plethysmography, bioimpedance, and skinfold measurement in
patients treated with these supplements.

- Compare the weight change in patients treated with these supplements.

OUTLINE: This is a randomized, double-blind, multicenter study. Patients are stratified
according to primary disease site (lung vs others), concurrent chemotherapy (yes vs no),
evidence of metastases (yes vs no), and degree of weight loss (2-5% vs 6-10%). Patients are
randomized to 1 of 2 treatment arms.

- Arm I: Patients receive oral Juven® supplement twice daily for 8 weeks.

- Arm II: Patients receive oral non-Juven® supplement twice daily for 8 weeks. All
patients undergo lean body mass measurement (to include multiple body composition and
weight change) and fatigue and quality of life assessments at baseline and then at 4
and 8 weeks.

PROJECTED ACCRUAL: A total of 468 patients (234 per treatment arm) will be accrued for this
study within 16 months.

Inclusion Criteria


DISEASE CHARACTERISTICS:

- Histologically or cytologically confirmed solid tumor or lymphoma with no leukemic
aspect

- Stage III or IV or any other stage associated with current metastatic disease at
presentation

- No primary or metastatic brain tumors

- Weight loss of at least 2% but no more than 10% within the past 3 months

- No ascites

PATIENT CHARACTERISTICS:

Age

- 17 and over

Performance status

- Zubrod 0-2

Life expectancy

- At least 3 months

Hematopoietic

- Not specified

Hepatic

- Not specified

Renal

- No hypercalcemia

Cardiovascular

- No persistent moderate or severe peripheral edema

- No uncontrolled congestive heart failure

Gastrointestinal

- No enteric fistula

- No concurrent intestinal obstruction

- Prior intestinal obstruction allowed

Other

- Not pregnant or nursing

- Negative pregnancy test

- No uncontrolled infections

- No other serious medical illness

- No metabolic disorder

PRIOR CONCURRENT THERAPY:

Biologic therapy

- Not specified

Chemotherapy

- Concurrent chemotherapy allowed

Endocrine therapy

- No dexamethasone as an appetite stimulant

- Intermittent dexamethasone during concurrent chemotherapy allowed

Radiotherapy

- Concurrent radiotherapy allowed

Surgery

- At least 1 week since prior minor surgery

- At least 3 weeks since prior major surgery

Other

- At least 30 days since prior total parenteral nutrition

- No concurrent parenteral feedings

- No concurrent known appetite stimulants (e.g., megestrol or dronabinol)

- No concurrent omega 3 fatty acids or their congeners (e.g., ProSure™)

- No concurrent amino acid supplements

- Concurrent use of other dietary supplements (e.g., Ensure® or Boost) is allowed

- Concurrent enteral feedings via PEG or nasogastric tube are allowed

Type of Study:

Interventional

Study Design:

Allocation: Randomized, Masking: Double-Blind, Primary Purpose: Supportive Care

Principal Investigator

Lawrence B. Berk, MD, PhD

Investigator Role:

Study Chair

Investigator Affiliation:

CCOP - Columbus

Authority:

United States: Federal Government

Study ID:

CDR0000269100

NCT ID:

NCT00053053

Start Date:

December 2002

Completion Date:

Related Keywords:

  • Cachexia
  • Lymphoma
  • Lymphoproliferative Disorder
  • Unspecified Adult Solid Tumor, Protocol Specific
  • unspecified adult solid tumor, protocol specific
  • cachexia
  • recurrent adult diffuse large cell lymphoma
  • recurrent adult diffuse mixed cell lymphoma
  • recurrent adult diffuse small cleaved cell lymphoma
  • recurrent adult Hodgkin lymphoma
  • recurrent adult immunoblastic large cell lymphoma
  • recurrent adult lymphoblastic lymphoma
  • recurrent cutaneous T-cell non-Hodgkin lymphoma
  • recurrent grade 1 follicular lymphoma
  • recurrent grade 2 follicular lymphoma
  • recurrent grade 3 follicular lymphoma
  • recurrent mantle cell lymphoma
  • stage III adult diffuse large cell lymphoma
  • stage III adult diffuse mixed cell lymphoma
  • stage III adult diffuse small cleaved cell lymphoma
  • stage III adult Burkitt lymphoma
  • stage III adult Hodgkin lymphoma
  • stage III adult immunoblastic large cell lymphoma
  • stage III adult lymphoblastic lymphoma
  • stage III cutaneous T-cell non-Hodgkin lymphoma
  • stage III grade 1 follicular lymphoma
  • stage III grade 2 follicular lymphoma
  • stage III grade 3 follicular lymphoma
  • stage III mantle cell lymphoma
  • stage IV adult diffuse large cell lymphoma
  • stage IV adult diffuse mixed cell lymphoma
  • stage IV adult diffuse small cleaved cell lymphoma
  • stage IV adult Burkitt lymphoma
  • stage IV adult Hodgkin lymphoma
  • stage IV adult immunoblastic large cell lymphoma
  • stage IV adult lymphoblastic lymphoma
  • stage IV cutaneous T-cell non-Hodgkin lymphoma
  • stage IV grade 1 follicular lymphoma
  • stage IV grade 2 follicular lymphoma
  • stage IV grade 3 follicular lymphoma
  • stage IV mantle cell lymphoma
  • intraocular lymphoma
  • AIDS-related peripheral/systemic lymphoma
  • recurrent adult Burkitt lymphoma
  • anaplastic large cell lymphoma
  • post-transplant lymphoproliferative disorder
  • recurrent marginal zone lymphoma
  • recurrent small lymphocytic lymphoma
  • stage III small lymphocytic lymphoma
  • stage III marginal zone lymphoma
  • stage IV small lymphocytic lymphoma
  • stage IV marginal zone lymphoma
  • extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue
  • nodal marginal zone B-cell lymphoma
  • splenic marginal zone lymphoma
  • Cachexia
  • Lymphoma
  • Lymphoma, Non-Hodgkin
  • Lymphoproliferative Disorders
  • Lymphoma, Large-Cell, Immunoblastic

Name

Location

Memorial Sloan-Kettering Cancer CenterNew York, New York  10021
University of Michigan Comprehensive Cancer CenterAnn Arbor, Michigan  48109-0752
Mayo Clinic Cancer CenterRochester, Minnesota  55905
Cardinal Bernardin Cancer Center at Loyola University Medical CenterMaywood, Illinois  60153-5500
MBCCOP - HawaiiHonolulu, Hawaii  96813
Barbara Ann Karmanos Cancer InstituteDetroit, Michigan  48201
Abington Memorial HospitalAbington, Pennsylvania  19001
Fox Chase Cancer CenterPhiladelphia, Pennsylvania  19111
CCOP - Upstate CarolinaSpartanburg, South Carolina  29303
University of Texas Health Science Center at San AntonioSan Antonio, Texas  78284-7811
CCOP - Atlanta RegionalAtlanta, Georgia  30342-1701
CCOP - Kansas CityKansas City, Missouri  64131
CCOP - Missouri Valley Cancer ConsortiumOmaha, Nebraska  68131
CCOP - Southern Nevada Cancer Research FoundationLas Vegas, Nevada  89106
CCOP - Christiana Care Health ServicesWilmington, Delaware  19899
CCOP - Mount Sinai Medical CenterMiami Beach, Florida  33140
CCOP - North Shore University HospitalManhasset, New York  11030
CCOP - Southeast Cancer Control ConsortiumWinston-Salem, North Carolina  27104-4241
Veterans Affairs Medical Center - Indianapolis (Roudebush)Indianapolis, Indiana  46202
CCOP - KalamazooKalamazoo, Michigan  49007-3731
CCOP - Metro-MinnesotaSaint Louis Park, Minnesota  55416
Veterans Affairs Medical Center - East OrangeEast Orange, New Jersey  07018-1095
Bloomington HospitalBloomington, Indiana  47402
Yale Comprehensive Cancer CenterNew Haven, Connecticut  06520-8028
St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical CenterGrand Junction, Colorado  81502
Methodist Cancer Center at Methodist HospitalIndianapolis, Indiana  46202
CCOP - Michigan Cancer Research ConsortiumAnn Arbor, Michigan  48106
Geisinger Medical CenterDanville, Pennsylvania  17822-0001
Penn State Cancer Institute at Milton S. Hershey Medical CenterHershey, Pennsylvania  17033-0850
Abramson Cancer Center of the University of PennsylvaniaPhiladelphia, Pennsylvania  19104-4283
Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical CenterLa Crosse, Wisconsin  54601
Marshfield Clinic - Marshfield CenterMarshfield, Wisconsin  54449
CCOP - OchsnerNew Orleans, Louisiana  70121
Rapid City Regional HospitalRapid City, South Dakota  57709
Comprehensive Cancer Center at Wake Forest UniversityWinston-Salem, North Carolina  27157-1082
Cancer Center at the University of VirginiaCharlottesville, Virginia  22908
Providence Saint Joseph Medical Center - BurbankBurbank, California  91505
Saint Agnes Cancer CenterFresno, California  93720
Sutter Health Western Division Cancer Research GroupGreenbrae, California  94904
Veterans Affairs Medical Center - Long BeachLong Beach, California  90822
CCOP - Bay Area Tumor InstituteOakland, California  94609-3305
O'Connor HospitalSan Jose, California  95128
CCOP - Santa Rosa Memorial HospitalSanta Rosa, California  95403
Memorial Hospital Cancer CenterColorado Springs, Colorado  80909
Florida Radiation Oncology GroupOrange Park, Florida  32073
Gulf Coast Cancer Treatment CenterPanama City, Florida  32405-4587
Sarasota Radiation and Medical Oncology CenterSarasota, Florida  34233
Northwest Community HospitalArlington Heights, Illinois  60005
Lutheran General Cancer Care CenterPark Ridge, Illinois  60068
Methodist Medical Center of IllinoisPeoria, Illinois  61636
CCOP - Central IllinoisSpringfield, Illinois  62526
Harbor Hospital CenterBaltimore, Maryland  21225
Cape Cod HospitalHyannis, Massachusetts  02601
Veterans Affairs Medical Center - Boston (Jamaica Plain)Jamaica Plain, Massachusetts  02130
CCOP - Cancer Research for the OzarksSpringfield, Missouri  65807
CCOP - Montana Cancer ConsortiumBillings, Montana  59101
Elliot Regional Cancer CenterManchester, New Hampshire  03103
John F. Kennedy Medical CenterEdison, New Jersey  08818
Newark Beth Israel Medical CenterNewark, New Jersey  07112
Community Medical CenterToms River, New Jersey  08755
New York Methodist HospitalBrooklyn, New York  11215-3609
CCOP - ColumbusColumbus, Ohio  43206
CCOP - DaytonKettering, Ohio  45429
Albert Einstein Cancer CenterPhiladelphia, Pennsylvania  19141
Mercy Hospital of PittsburghPittsburgh, Pennsylvania  15219
Reading Hospital and Medical CenterReading, Pennsylvania  19612-6052
Mercy Hospital Cancer Center - ScrantonScranton, Pennsylvania  18501
CCOP - MainLine HealthWynnewood, Pennsylvania  19096
CCOP - GreenvilleGreenville, South Carolina  29615
Harrington Cancer CenterAmarillo, Texas  79106
University of Texas Medical BranchGalveston, Texas  77555-1329
Joe Arrington Cancer Research and Treatment CenterLubbock, Texas  79410-1894
Dixie Regional Medical CenterSaint George, Utah  84770
LDS HospitalSalt Lake City, Utah  84143
Deaconess Medical CenterSpokane, Washington  99210-0248
Yakima Valley Memorial HospitalYakima, Washington  98902
St. Vincent HospitalGreen Bay, Wisconsin  54307-3508
University of Wisconsin Comprehensive Cancer CenterMadison, Wisconsin  53792
Community Memorial HospitalMenomonee Falls, Wisconsin  53051
Veterans Affairs Medical Center - Milwaukee (Zablocki)Milwaukee, Wisconsin  53295
University of Colorado Cancer Center at University of Colorado Health Sciences CenterDenver, Colorado  80010
University of Miami Sylvester Comprehensive Cancer CenterMiami, Florida  33136
CCOP - Northern Indiana CR ConsortiumSouth Bend, Indiana  46601
Ellis Fischel Cancer Center at University of Missouri - ColumbiaColumbia, Missouri  65203
Siteman Cancer Center at Barnes-Jewish HospitalSaint Louis, Missouri  63110
Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical CenterLebanon, New Hampshire  03756-0002
Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel HillChapel Hill, North Carolina  27599-7570
Charles M. Barrett Cancer Center at University HospitalCincinnati, Ohio  45267-0526
Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State UniversityColumbus, Ohio  43210-1240
CCOP - Columbia River Oncology ProgramPortland, Oregon  97225
Kimmel Cancer Center at Thomas Jefferson University - PhiladelphiaPhiladelphia, Pennsylvania  19107
Vanderbilt-Ingram Cancer Center at Vanderbilt Medical CenterNashville, Tennessee  37232-2516
CCOP - Scott and White HospitalTemple, Texas  76508
Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsBaltimore, Maryland  21231-2410
CCOP - St. Vincent Hospital Cancer Center, Green BayGreen Bay, Wisconsin  54301
Cleveland Clinic Taussig Cancer CenterCleveland, Ohio  44195
MBCCOP - Gulf CoastMobile, Alabama  36688
USC/Norris Comprehensive Cancer Center and HospitalLos Angeles, California  90033-0804
MBCCOP - LSU Health Sciences CenterNew Orleans, Louisiana  70112
Naval Medical Center - San DiegoSan Diego, California  92134-3202
CCOP - Syracuse Hematology-Oncology Associates of Central New York, P.C.Syracuse, New York  13217
CCOP - OklahomaTulsa, Oklahoma  74136
Utah Valley Regional Medical Center - ProvoProvo, Utah  84604
Foundation for Cancer Research and EducationPhoenix, Arizona  85013
Bay Medical CenterPanama City, Florida  32401
Peninsula Regional Medical CenterSalisbury, Maryland  21801
MidMichigan Medical Center - MidlandMidland, Michigan  48670
Monmouth Medical CenterLong Branch, New Jersey  07740-6395
University of Utah Health Sciences CenterSalt Lake City, Utah  84132
Dana-Farber/Harvard Cancer Center at Dana Farber Cancer InstituteBoston, Massachusetts  02115
City of Hope Comprehensive Cancer CenterDuarte, California  91010
UCSF Comprehensive Cancer CenterSan Francisco, California  94115
CCOP - BeaumontRoyal Oak, Michigan  48073-6769
Hillman Cancer Center at University of Pittsburgh Cancer InstitutePittsburgh, Pennsylvania  15236
Markey Cancer Center at University of Kentucky Chandler Medical CenterLexington, Kentucky  40536-0084
Tulane Cancer Center at Tulane University Hospital and ClinicNew Orleans, Louisiana  70112
Cancer Research Center at Boston Medical CenterBoston, Massachusetts  02118
Herbert Irving Comprehensive Cancer Center at Columbia UniversityNew York, New York  10032
James Graham Brown Cancer Center at University of LouisvilleLouisville, Kentucky  40202
Roger Williams Medical CenterProvidence, Rhode Island  02908-4735
Fairview University Medical Center - University CampusMinneapolis, Minnesota  55455
SUNY Downstate Medical CenterBrooklyn, New York  11203
McDowell Cancer Center at Akron General Medical CenterAkron, Ohio  44307
Ireland Cancer Center at University Hospitals of Cleveland and Case Western Reserve UniversityCleveland, Ohio  44106
Oklahoma University Medical CenterOklahoma City, Oklahoma  73104
M.D. Anderson Cancer Center at University of TexasHouston, Texas  77030
DCH Cancer Treatment CenterTuscaloosa, Alabama  35401
Radiation Medical Group, IncorporatedSan Diego, California  92101
Holmes Regional Medical CenterMelbourne, Florida  32901-3276
Regional Radiation Oncology Center at RomeRome, Georgia  30165
Central Baptist HospitalLexington, Kentucky  40503
Riverhill Radiation OncologyYonkers, New York  10701
Trinity Cancer Care CenterMinot, North Dakota  58701
CCOP - Toledo Community HospitalToledo, Ohio  43623-3456
St. Luke's Hospital Cancer CenterBethlehem, Pennsylvania  18015
Mercy Fitzgerald HospitalDarby, Pennsylvania  19023
Wilford Hall Medical CenterLackland Air Force Base, Texas  78236-5300
RMH Regional Cancer CenterHarrisonburg, Virginia  22801
Waukesha Memorial Hospital Regional Cancer CenterWaukesha, Wisconsin  53188
Comprehensive Cancer Center at University of Alabama at BirminghamBirmingham, Alabama  35294
Loma Linda University Cancer Institute at Loma Linda University Medical CenterLoma Linda, California  92354
University of Florida Shands Cancer CenterGainesville, Florida  32610-0232
Baptist-South Miami Regional Cancer ProgramMiami, Florida  33176
Winship Cancer Institute of Emory UniversityAtlanta, Georgia  30322
Alvin and Lois Lapidus Cancer Institute at Sinai HospitalBaltimore, Maryland  21215
SUNY Upstate Medical University HospitalSyracuse, New York  13210
Naval Medical Center - PortsmouthPortsmouth, Virginia  23708-2197
Massey Cancer Center at Virginia Commonwealth UniversityRichmond, Virginia  23298-0037
Methodist Hospital Cancer Center at Nebraska Methodist Hospital - OmahaOmaha, Nebraska  68114-4199
CCOP - Marshfield Clinic Research FoundationMarshfield, Wisconsin  54449
James P. Wilmot Cancer Center at University of Rochester Medical CenterRochester, New York  14642
Comprehensive Cancer InstituteHuntsville, Alabama  35801
Torrance Memorial Medical CenterTorrance, California  90505
Sibley Memorial HospitalWashington, District of Columbia  20016
21st Century Oncology - Fort MyersFort Myers, Florida  33901-8082
Tallahassee Memorial HospitalTallahassee, Florida  32308
Oncology Institute of Greater LafayetteLafayette, Indiana  47904
Cancer Center at Lexington ClinicLexington, Kentucky  40504
St. Agnes Cancer CenterBaltimore, Maryland  21229
Lourdes Regional Cancer CenterBinghamton, New York  13905
North Shore Radiation OncologySetauket, New York  11733
Batte Cancer Center at Northeast Medical CenterConcord, North Carolina  28025
Cancer Center at Christ HospitalCincinnati, Ohio  45219
Parma Community General HospitalParma, Ohio  44129
Vermont Cancer Center at University of VermontBurlington, Vermont  05405-0075
Cancer Institute at Virginia Mason Medical CenterSeattle, Washington  98111
William Beaumont Hospital - Royal Oak CampusRoyal Oak, Michigan  48073
Fox Chase Virtua Health Cancer Program - MarltonMarlton, New Jersey  08053
Greenebaum Cancer Center at University of Maryland Medical CenterBaltimore, Maryland  21201
Josephine Ford Cancer Center at Henry Ford Health SystemDetroit, Michigan  48202
UNMC Eppley Cancer Center at the University of Nebraska Medical CenterOmaha, Nebraska  68198-7680
Jonsson Comprehensive Cancer Center at UCLALos Angeles, California  90095-1781
Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical SchoolNew Brunswick, New Jersey  08903
General Robert Huyser Cancer Center at David Grant Medical CenterTravis Air Force Base, California  94535
Leo W. Jenkins Cancer Center at Pitt County Memorial HospitalGreenville, North Carolina  27858-4354
Robert H. Lurie Comprehensive Cancer Center at Northwestern UniversityChicago, Illinois  60611
Maine Medical Center - Bramhall CampusPortland, Maine  04102
Mount Diablo Regional Cancer CenterConcord, California  94524-4110
Ingalls Cancer Care Center at Ingalls Memorial HospitalHarvey, Illinois  60426
Mary Bird Perkins Cancer Center - Baton RougeBaton Rouge, Louisiana  70809
Upper Michigan Cancer Center at Marquette General HospitalMarquette, Michigan  49855
Fox Chase Cancer Center at St. Francis Medical CenterTrenton, New Jersey  08629
Delaware County Regional Cancer Center at Delaware County Memorial HospitalDrexel Hill, Pennsylvania  19026
DeCesaris Cancer Institute at Anne Arundel Medical CenterAnnapolis, Maryland  21401
California Cancer Center - Woodward Park OfficeFresno, California  93720
H. Lee Moffitt Cancer Center and Research Institute at University of South FloridaTampa, Florida  33612
Cancer Center at Ball Memorial HospitalMuncie, Indiana  47303
Wendt Regional Cancer Center at Finley HospitalDubuque, Iowa  52001
Merle M. Mahr Cancer Center at Regional Medical Center of Hopkins CountyMadisonville, Kentucky  42431
Great Lakes Cancer Institute at McLaren Regional Medical CenterFlint, Michigan  48532
South Jersey Healthcare Regional Cancer CenterMillville, New Jersey  08332
Atlantic City Medical Center - Mainland DivisionPomona, New Jersey  08240
Akron City Hospital at Summa Health SystemAkron, Ohio  44304
LaFortune Cancer Center at St. John Health SystemTulsa, Oklahoma  74104
John and Dorothy Morgan Cancer Center at Lehigh Valley HospitalAllentown, Pennsylvania  18105
Allegheny Cancer Center at Allegheny General HospitalPittsburgh, Pennsylvania  15212
Western Pennsylvania Cancer Institute at Western Pennsylvania HospitalPittsburgh, Pennsylvania  15224-1791
Bon Secours Cancer Care at St. Mary's HospitalRichmond, Virginia  23226
Vince Lombardi Cancer Clinic at St. Luke's Medical CenterMilwaukee, Wisconsin  53215
All Saints Cancer Center at All Saints HealthcareRacine, Wisconsin  53405
Schiffler Cancer Center at Wheeling HospitalWheeling, West Virginia  26003
Saint Louis University Cancer CenterSaint Louis, Missouri  63110
Huntington Cancer Center at Huntington HospitalPasadena, California  91105
St. Joseph's Regional Cancer CenterStockton, California  95204
Robert and Beverly Lewis Family Cancer Care Center at Pomona Valley Hospital Medical CenterPomona, California  91767
Hospital of Saint RaphaelNew Haven, Connecticut  06511
St. John's Cancer Center at St. John's Medical CenterAnderson, Indiana  46016
York Cancer Center at Wellspan HealthYork, Pennsylvania  17403
Community Cancer Center at Rutland Regional Medical CenterRutland, Vermont  05701
Frank C. Love Cancer Institute at St. Anthony HospitalOklahoma City, Oklahoma  73101
Montgomery Cancer CenterMontgomery, Alabama  36106-3657
Radiation Oncology Centers - SacramentoSacramento, California  95816
Louisville Radiation Oncology Center at Caritas Regional Cancer CenterLouisville, Kentucky  40215
Beth Israel Medical Center - Philipps Ambulatory Care CenterNew York, New York  10003
Wilkes-Barre General HospitalWilkes-Barre, Pennsylvania  18764-0001
West Tennessee Cancer Center at Jackson-Madison County General HospitalJackson, Tennessee  38301
Cancer Center at Greater Baltimore Medical CenterBaltimore, Maryland  21204
Valley Hospital - RidgewoodRidgewood, New Jersey  07450
Esther Marie Hatton Cancer Care Center at St. Elizabeth Medical CenterEdgewood, Kentucky  41017
Dale and Frances Hughes Cancer Center at Pocono Medical CenterEast Stroudsburg, Pennsylvania  18301
John B. Amos Community Cancer CenterColumbus, Georgia  31902
NSMC Cancer Center - PeabodyPeabody, Massachusetts  01960
Fitzpatrick Cancer Center at Champlain Valley Physicians Hospital Medical CenterPlattsburgh, New York  12901
William Beaumont Hospital - Troy CampusTroy, Michigan  48085
University Medical Center at PrincetonPrinceton, New Jersey  08540
Associated Radiologists, P.A. at Warren Radiation Therapy CenterWarren, New Jersey  07059
Radiation Oncology Associates, PAAlbuquerque, New Mexico  87109
Finger Lakes Radiation Oncology Center at Clifton Springs Hospital and clinicClifton Springs, New York  14432
Arlington Cancer Center - ArlingtonArlington, Texas  76012
Columbia St. Mary's - Columbia CampusMilwaukee, Wisconsin  53211