Acupuncture for the Treatment of Pancreatic Cancer Pain: A Single Arm Phase II Study
- Assess the effects of acupuncture and acupressure on pain, sedation, and use of opiate
medication in patients with moderate or severe pain related to stage III or IV
- Determine whether controlled trials of this therapy are warranted in this patient
- Provide data to aid design of further warranted studies of this therapy in this patient
OUTLINE: Patients receive acupuncture treatment comprising 20 minutes of needle insertion
into the arms and abdomen to the depth used in traditional Chinese medicine on approximately
days 4, 7, 11, and 14. After each acupuncture treatment, the acupuncturist applies/reapplies
acupressure devices by inserting 2-6 smaller needles (studs) into the abdomen (which are
held in place with surgical tape) and taping tiny metal balls to 3 points in each ear.
Patients or caregivers are instructed to administer acupressure by pressing on the ear
points (metal balls) for 1-2 minutes per point and moving the semi-permanent abdominal
needles in small circular movements with the fingers, at a rate of 2-3 cycles per second,
for 1-2 minutes per point, upon waking in the morning and in the early afternoon. Patients
or caregivers are also instructed to stimulate a "rescue point" (the Shenmen auricular
point) if patients experience pain exacerbations at other times during the day. Patients who
respond well to acupuncture are offered further treatment.
Pain is assessed using the numerical rating scale on approximately days 1-4, 7, 11, and
14-17. Sedation is assessed using the Profile of Mood States (POMS) on approximately days 3
and 17. Analgesic medication use is assessed on approximately days 1-3 and 15-17.
PROJECTED ACCRUAL: A total of 10-29 patients will be accrued for this study within
approximately 2 years.
Primary Purpose: Supportive Care
Barrie R. Cassileth, PhD
Memorial Sloan-Kettering Cancer Center
United States: Federal Government
|Memorial Sloan-Kettering Cancer Center||New York, New York 10021|