Inclusion Criteria

DISEASE CHARACTERISTICS:

- Histologically confirmed incurable primary or metastatic solid tumor or non-Hodgkin's
lymphoma

- Relapsed after or is refractory (e.g., unresectable) to at least 2 standard
chemotherapy regimens and rituximab

- No standard curative surgery, chemotherapy, immunotherapy, other antitumor
therapy, or radiotherapy options exist

- No known or suspected squamous cell carcinoma of the lung

- No prior or concurrent CNS (brain or leptomeningeal) metastases

- No prior or concurrent primary intracranial tumor by MRI or CT scan

PATIENT CHARACTERISTICS:

Age:

- 25 and over

Performance status:

- ECOG 0-2

Life expectancy:

- Not specified

Hematopoietic:

- WBC at least 3,500/mm^3

- Absolute neutrophil count at least 1,500/mm^3

- Platelet count at least 100,000/mm^3

- Hemoglobin at least 9.0 g/dL

- No other severe or uncontrolled hematologic condition

Hepatic:

- Bilirubin no greater than 1.5 times upper limit of normal (ULN)

- AST and ALT no greater than 2 times ULN

- Alkaline phosphatase no greater than 2 times ULN

- PT, PTT, and INR normal

Renal:

- Creatinine no greater than ULN

- No 1+ or greater proteinuria

- No other severe or uncontrolled renal condition

Cardiovascular:

- Electrocardiogram normal

- LVEF normal by echocardiogram or MUGA scan within the past 12 months or since
completion of prior anthracycline

- No severe or uncontrolled cardiovascular condition

- No New York Heart Association class III or IV heart disease

- No active coronary artery disease, angina, congestive heart failure, or arrhythmia

- No myocardial infarction within the past 6 months

- No prior or concurrent peripheral vascular disease, including:

- Angiographically or ultrasonographically documented arterial or venous occlusive
event

- Symptomatic claudication

- No untreated or uncontrolled hypertension

- No treated blood pressure more than 160/100 mm Hg on at least 3 repeated
determinations on separate days within the past 6 weeks

- No symptomatic orthostatic hypotension

Pulmonary:

- No severe or uncontrolled pulmonary condition

- No pulmonary embolism

Other:

- No prior hypersensitivity reactions to any recombinant proteins (e.g., VEGF Trap)

- No severe or uncontrolled gastrointestinal, immunological, or musculoskeletal
condition

- No severe or uncontrolled psychiatric or adverse social circumstance that would
preclude study

- No active infection requiring antibiotics

- HIV negative

- Not pregnant or nursing

- Negative pregnancy test

- Fertile patients must use effective double-barrier contraception during and for at
least 3 months after study

PRIOR CONCURRENT THERAPY:

Biologic therapy:

- See Disease Characteristics

- At least 3 weeks since prior immunotherapy

- No concurrent epoetin alfa, filgrastim (G-CSF), or sargramostim (GM-CSF)

Chemotherapy:

- See Disease Characteristics

- At least 3 weeks since prior chemotherapy

Endocrine therapy:

- No concurrent adrenal corticosteroids, except low doses as replacement therapy in
patients who have previously received suppressive doses or for adrenal insufficiency

- No concurrent systemic hormonal contraceptive agents

Radiotherapy:

- See Disease Characteristics

- At least 3 weeks since prior radiotherapy

Surgery:

- See Disease Characteristics

- At least 3 weeks since prior surgery (except fine needle biopsy/aspiration or
removal/biopsy of a skin lesion)

- No prior surgical procedure for correction or prophylaxis of peripheral vascular
insufficiency or cerebral ischemic events

Other:

- Recovered from prior therapy

- At least 6 months since prior treatment for acute congestive heart failure

- At least 30 days since prior investigational drugs

- No concurrent standard or other investigational anticancer agents

- No concurrent herbal supplements ("nutraceuticals")

- No concurrent anticoagulant or antiplatelet drugs, (e.g., warfarin, heparin, aspirin,
or other non-steroidal anti-inflammatory drugs) except selective cyclo-oxygenase-2
(COX-2) inhibitors for analgesia

- No concurrent COX-2 inhibitors for tumor treatment or prophylaxis