Collection of Peripheral Blood and/or Urine From Patients Undergoing Radiation Therapy
Evolving research initiatives in the Radiation Oncology Branch (ROB) and the Radiation
Oncology Sciences Program (ROSP), NCI, depend upon the availability of blood and urine
samples from patients receiving radiotherapy.
Examples of planned studies include an exploration of the effects of radiotherapy on
peripheral blood lymphocyte gene expression, evaluation of cytogenetic damage in immature
red blood cells, and measurements of matrix metalloproteinases (MMP) in urine.
This protocol provides a means of acquiring blood and urine samples in patients receiving
radiation therapy for a variety of conditions.
Patients seen in the radiation oncology clinic will be asked to donate blood and/or urine
before, during and after their treatment
This is a pilot, exploratory study to evaluate the effects of ionizing radiation in blood
and/ or urine.
On most occasions, the blood samples will be obtained as a component of routine patient
monitoring and will not necessitate an additional venipuncture.
Blood and urine samples will be processed and stored in the Radiation Oncology Branch and
Basic Research Laboratory, CCR, NCI, for use in the research efforts of the branch.
Kevin A Camphausen, M.D.
National Cancer Institute (NCI)
United States: Federal Government
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