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A Pilot Study to Investigate the Clinical Utility of the Peregrine Monte Carlo Dose Calculation System for Radiation Therapy Treatment Planning


Phase 2
N/A
N/A
Not Enrolling
Both
Neoplasm

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Trial Information

A Pilot Study to Investigate the Clinical Utility of the Peregrine Monte Carlo Dose Calculation System for Radiation Therapy Treatment Planning


The utility of PEREGRINE Monte Carlo calculations for radiation treatment planning in a
clinical setting will be assessed by comparing results with other fully three-dimensional
programs. ROB will investigate PEREGRINE for clinical use at NCI.

Inclusion Criteria


INCLUSION CRITERIA:

Patients with documented malignancy requiring standard radiotherapy OR patients with a
benign condition for whom radiotherapy is indicated.

EXCLUSION CRITERIA:

Documented connective tissue disease or Ataxia Telangiectasia.

Cognitively impaired patients who cannot give informed consent.

Other medical conditions deemed by the PI to make the patient ineligible.

Patients requiring emergent radiotherapy.

Patients who are not able to undergo a CT scan.

Type of Study:

Interventional

Study Design:

Endpoint Classification: Safety/Efficacy Study, Primary Purpose: Treatment

Authority:

United States: Federal Government

Study ID:

990116

NCT ID:

NCT00026936

Start Date:

May 1999

Completion Date:

January 2005

Related Keywords:

  • Neoplasm
  • External Beam Radiotherapy
  • TCP
  • DVH
  • NTCP
  • 3-D Programming
  • Neoplasms

Name

Location

National Cancer Institute (NCI)Bethesda, Maryland  20892