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The Seroprevalence of Kaposi's Sarcoma Herpesvirus in the United States


N/A
N/A
N/A
Not Enrolling
Both
Kaposi's Sarcoma, Herpesviridae Infection

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Trial Information

The Seroprevalence of Kaposi's Sarcoma Herpesvirus in the United States


Kaposi sarcoma herpesvirus (KSHV) is the viral cause of Kaposi sarcoma. Although infection
with this virus appears to be uncommon in the United States, the prevalence in the general
population in uncertain, and routes for transmission are poorly characterized. This study
makes use of questionnaire data and serum specimens obtained in the third National Health
and Nutrition Survey (NHAnes III). Sera from 18,168 individuals in this study were tested
for antibodies to the KSHV proteins K8.1 and LANA. We will use these measurements to
estimate KSHV seroprevalence for the overall U.S. general population and for demographic
subgroups. To characterize potential transmission routes, we will also examine whether KSHV
seroprevalence is related to sexual activity and exposures to blood, as indicated by
responses to questionnaire items and previous NHANES III measurements of markers of relevant
viral infections.

Inclusion Criteria


- No specific eligibility criteria was provided for this protocol.

Type of Study:

Observational

Study Design:

N/A

Authority:

United States: Federal Government

Study ID:

010073

NCT ID:

NCT00026728

Start Date:

February 2001

Completion Date:

December 2005

Related Keywords:

  • Kaposi's Sarcoma
  • Herpesviridae Infection
  • Human Herpesvirus B
  • NHANES
  • Epidemiology
  • Population-Based Study
  • Kaposi's Sarcoma Herpes Virus
  • Herpesviridae Infections
  • Sarcoma, Kaposi
  • Sarcoma

Name

Location

National Cancer Institute (NCI)Bethesda, Maryland  20892