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The Use Of Multiple CT Scans To Reduce Target Positioning Errors In Patients Undergoing External Beam Radiotherapy Treatment For Prostate Cancer


Phase 2
N/A
N/A
Not Enrolling
Male
Prostate Cancer

Thank you

Trial Information

The Use Of Multiple CT Scans To Reduce Target Positioning Errors In Patients Undergoing External Beam Radiotherapy Treatment For Prostate Cancer


OBJECTIVES:

- Compare the accuracy of radiotherapy delivery using multiple CT scans to guide patient
positioning vs the standard portal image guided procedure in patients with prostate
cancer undergoing external beam radiotherapy.

- Determine the reduction in the proportion of patients with large target positioning
errors using the CT-guided procedure.

- Determine organ motion and setup errors over the course of radiotherapy in order to
develop efficient clinical intervention strategies in these patients.

OUTLINE: Patients undergo radiotherapy over 9 weeks. Patients undergo a CT scan immediately
prior to receiving radiotherapy on treatment days 3-8 and then weekly thereafter. On 3
different days, patients also undergo CT scan immediately after radiotherapy. If the CT
scans indicate a correction that exceeds the action level currently in effect, then
beginning with the next treatment, the patient's position with respect to the radiation
field is adjusted.

PROJECTED ACCRUAL: A total of 25 patients will be accrued for this study within 2 years.

Inclusion Criteria


DISEASE CHARACTERISTICS:

- Undergoing external beam intensity-modulated radiotherapy for prostate cancer

- Able to maintain treatment position for about 40 minutes

PATIENT CHARACTERISTICS:

Age:

- Not specified

Performance status:

- Not specified

Life expectancy:

- Not specified

Hematopoietic:

- Not specified

Hepatic:

- Not specified

Renal:

- Not specified

PRIOR CONCURRENT THERAPY:

Biologic therapy:

- Not specified

Chemotherapy:

- Not specified

Endocrine therapy:

- Not specified

Radiotherapy:

- See Disease Characteristics

Surgery:

- Not specified

Type of Study:

Interventional

Study Design:

Primary Purpose: Diagnostic

Outcome Measure:

Treatment accuracy

Safety Issue:

No

Principal Investigator

Michael Lovelock, PhD

Investigator Role:

Study Chair

Investigator Affiliation:

Memorial Sloan-Kettering Cancer Center

Authority:

United States: Federal Government

Study ID:

01-022

NCT ID:

NCT00020891

Start Date:

March 2001

Completion Date:

Related Keywords:

  • Prostate Cancer
  • stage I prostate cancer
  • stage IIB prostate cancer
  • stage IIA prostate cancer
  • stage III prostate cancer
  • stage IV prostate cancer
  • recurrent prostate cancer
  • Prostatic Neoplasms

Name

Location

Memorial Sloan-Kettering Cancer CenterNew York, New York  10021