Phase I Pilot Study of Stereotaxic Radiosurgery in Patients With Intracranial Neoplasms
OBJECTIVES: I. Establish stereotaxic radiosurgery as a treatment technique at the National
Institute of Health in patients with intracranial neoplasms.
II. Assess the response rate, local control, time to progression, pattern of failure, and
magnetic resonance spectrographic data following this therapy in these patients.
PROTOCOL OUTLINE: All patients undergo stereotaxic head frame placement, followed by
stereotaxic radiosurgery on day 1. The dosage of radiation therapy administered is dependent
on the tumor diameter.
Patients are followed at 2 and 6 weeks and then every 3 months for 5 years.
Up to 30 patients will be accrued for this study within 7-10 months.
Primary Purpose: Treatment
Brian G. Fuller
National Cancer Institute (NCI)
United States: Federal Government
|Radiation Oncology Branch||Bethesda, Maryland 20892|