Inclusion Criteria

DISEASE CHARACTERISTICS: Histologically confirmed small cell lung cancer Must have
completed initial therapy with or without radiotherapy and have achieved a complete
response or partial response to therapy without subsequent evidence of disease progression
Must have completed any radiotherapy including prophylactic cranial radiotherapy as part
of the planned primary therapy

PATIENT CHARACTERISTICS: Age: 18 and over Performance status: Karnofsky 70-100% Life
expectancy: Not specified Hematopoietic: WBC at least 3,000/mm3 Lymphocyte count at least
500/mm3 Hepatic: Bilirubin no greater than 1.5 mg/dL SGOT no greater than 1.5 times upper
limit of normal (ULN) Alkaline phosphatase no greater than 1.5 times ULN Renal: Not
specified Cardiovascular: No New York Heart Association class III or IV heart disease
Other: No known immunodeficiency or autoimmune disease No other active malignancies within
the past 5 years except nonmelanoma skin cancer No clinically significant peripheral
neuropathy Not pregnant or nursing Negative pregnancy test Fertile patients must use
effective contraception

PRIOR CONCURRENT THERAPY: Biologic therapy: See Disease Characteristics At least 4 weeks
but no more than 12 weeks since prior initial therapy and recovered Chemotherapy: See
Disease Characteristics At least 4 weeks but no more than 12 weeks since prior initial
therapy and recovered Endocrine therapy: See Disease Characteristics At least 4 weeks but
no more than 12 weeks since prior initial therapy and recovered No concurrent
corticosteroids Radiotherapy: See Disease Characteristics At least 4 weeks but no more
than 12 weeks since prior initial therapy and recovered No prior radiotherapy to the
spleen Surgery: No prior splenectomy