The Utility of Positron Emission Tomography (PET) in Staging of Patients With Potentially Operable Non-Small Cell Lung Carcinoma
- Determine the efficacy of fludeoxyglucose F 18 positron emission tomography (FDG-PET)
in detecting lesions that would preclude pulmonary resection in patients with non-small
cell lung cancer.
OUTLINE: This is a multicenter study.
Patients receive fludeoxyglucose F 18 (FDG) IV followed 45-60 minutes later by positron
emission tomography (PET) imaging. Confirmatory studies, such as biopsy, fine needle
aspiration, or other imaging studies are then conducted to confirm the PET findings.
Patients with no mediastinal nodal or distant metastases identified by FDG-PET scan may
undergo thoracotomy and pulmonary resection within 1 month of evaluation.
Patients are followed at 5-6 months after surgery.
PROJECTED ACCRUAL: A total of 120-235 patients will be accrued for this study.
Primary Purpose: Diagnostic
Carolyn E. Reed, MD
Medical University of South Carolina
United States: Federal Government
|Memorial Sloan-Kettering Cancer Center||New York, New York 10021|
|Jonsson Comprehensive Cancer Center, UCLA||Los Angeles, California 90095-1781|
|University of Chicago Cancer Research Center||Chicago, Illinois 60637|
|Indiana University Cancer Center||Indianapolis, Indiana 46202-5265|
|Duke Comprehensive Cancer Center||Durham, North Carolina 27710|
|Medical University of South Carolina||Charleston, South Carolina 29425-0721|
|Mount Sinai School of Medicine||New York, New York 10029|
|UCSF Cancer Center and Cancer Research Institute||San Francisco, California 94115-0128|
|Barnes-Jewish Hospital||Saint Louis, Missouri 63110|
|Massachusetts General Hospital Cancer Center||Boston, Massachusetts 02114|
|Massey Cancer Center||Richmond, Virginia 23298-0037|
|Holden Comprehensive Cancer Center||Iowa City, Iowa 52242-1009|
|Allegheny General Hospital||Pittsburgh, Pennsylvania 15212-4772|
|William Beaumont Hospital||Royal Oak, Michigan 48073|
|Marlene and Stewart Greenebaum Cancer Center, University of Maryland||Baltimore, Maryland 21201-1595|
|Lutheran General Hospital||Park Ridge, Illinois 60068|
|Latter Day Saints Hospital||Salt Lake City, Utah 84143|
|Western Pennsylvania Cancer Institute||Pittsburgh, Pennsylvania 15224|
|Morton Plant Mease Health Care||Clearwater, Florida 33756|
|Jameson Memorial Hospital||New Castle, Pennsylvania 16105|
|Lakeland Regional Medical Center||Lakeland, Florida 33804|
|Veterans Affairs Medical Center - Iowa City||Iowa City, Iowa 52246-2208|
|Westmoreland Hospital||Greensburg, Pennsylvania 15601-2282|