A Phase II Trial of Hyperthermia and Radiotherapy for Locally Advanced Adenocarcinoma of the Prostate
- Evaluate the efficacy of hyperthermia and radiation therapy in patients with locally
advanced prostate cancer.
- Evaluate the acute and long term toxicities of these therapies in this patient
OUTLINE: Patients are treated with external beam irradiation 5 days a week for a total of
approximately 7 weeks. Hyperthermia treatment is given twice in the first 4 weeks of
radiation therapy, preferably early in the course of radiation. Hyperthermia treatments are
only given once a week. A transrectal ultrasound applicator is used to deliver the
Patients are followed every three months for 2 years, and every 6 months thereafter.
PROJECTED ACCRUAL: Approximately 65 patients will be accrued over 2 years.
Primary Purpose: Treatment
Mark Hurwitz, MD
Dana-Farber Cancer Institute
United States: Federal Government
|Joint Center for Radiation Therapy||Boston, Massachusetts 02215|
|Dana-Farber Cancer Institute||Boston, Massachusetts 02115|