Inclusion Criteria

DISEASE CHARACTERISTICS: Histologically confirmed stage III/IV ovarian epithelial cancer
in first or second clinical complete remission after receiving a minimum of 4-10 courses
of chemotherapy consisting of paclitaxel and either cisplatin or carboplatin Ovarian
epithelial cancer of following histologic types: Serous adenocarcinoma Mucinous
adenocarcinoma Clear cell adenocarcinoma Transitional cell Adenocarcinoma N.O.S.
Endometrioid adenocarcinoma Undifferentiated carcinoma Mixed epithelial carcinoma
Malignant Brenner's Tumor Remission stability maintained for at least 4 weeks Protocol
therapy must begin 30-90 days after last dose of standard therapy No active pleural or
pericardial effusion No prior/concurrent brain metastasis or carcinoid meningitis

PATIENT CHARACTERISTICS: Age: 18 to 60 Performance status: Karnofsky 70-100% Life
expectancy: Not specified Hematopoietic: Not specified Hepatic: Bilirubin less than 1.5
times the upper limit of normal (ULN) SGOT or SGPT less than 2.0 times ULN Albumin greater
than 2.0 g/dL Renal: Creatinine clearance greater than 60 mL/min Cardiovascular: Ejection
fraction greater than 45% by MUGA Pulmonary: If history of smoking or abnormal lung
function, Diffusion capacity greater than 50% (corrected) A-a gradient less than 20 Other:
No history of hemorrhagic cystitis No second malignancy within the last 5 years except
basal cell skin cancer HIV negative No chronic active hepatitis B No hepatitis C No
history of Aspergillus infection

PRIOR CONCURRENT THERAPY: Biologic therapy: No prior stem cell transplant Chemotherapy:
Prior chemotherapy consisting of paclitaxel and either cisplatin or carboplatin Endocrine
therapy: Not specified Radiotherapy: No prior radiation therapy for malignancy (excluding
chest wall radiation therapy for breast cancer) Surgery: Not specified